Seattle Structural Genomics Center for Infectious Diseases – Year XI
EMSL Project ID
50089
Abstract
A potential consequence of rapid climate change is the emergence of epidemic infectious zoonotic diseases as the habitats of disease carriers change to expose human populations to new infectious agents. These environmental changes, along with the emergence of multi-drug resistant strains, makes developing new drugs to combat emerging and re-emerging infectious diseases of upmost importance. The National Institute of Allergy and Infectious Diseases (NIAID) has identified the need to prepare a library of three-dimensional protein structures of potential drug targets that may be used for the structure-based design of new drugs. Towards populating this library NIAID has established two structural genomics centers: The Center for Structural Genomics of Infectious Disease (CSGID) and the Seattle Structural Genomics Center for Infectious Disease (SSGCID). The high-field suite of NMR spectrometers at EMSL will assist the population of the structure library with the high-field NMR data used to determine the solution structure for 2-3 proteins identified as potential drug targets.
Project Details
Start Date
2017-10-23
End Date
2018-09-30
Status
Closed
Released Data Link
Team
Principal Investigator