Characterization of cell-to-cell communication through the secreted metabolomes of microbial communities
EMSL Project ID
50137
Abstract
Inter-cellular communication is a complex process that plays a pivotal role in the microbiome and is essential for our understanding of microbial dynamics and functional roles. Teasing apart individual contributions to the immense network of interactions within a microbial community is hindered by our inability to assign molecular signals to a single participant. Here, we aim to further develop and validate a custom 3D printed platform that will allow us to record the small molecules that a microorganism makes in response to other organisms and signals within its environment. Using this information, we plan to develop methods to infer the context-specific language of microbial communication for a panel of environmentally relevant microorganisms. The goal of this Rapid Access proposal is to characterize our platform and develop preliminary data that will serve as the basis for future grant proposals.Project Details
Project type
Limited Scope
Start Date
2018-03-20
End Date
2018-05-20
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members