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Yarrowia lipolytica for biotechnology and synthetic biology


EMSL Project ID
50152

Abstract

The team at PNNL is using a combination of flow cytometry, microscopy and lipidomics to establish baseline cell biological and metabolite data on lipid production by the W29 strain of Yarrowia lipolytica. It is important to understand the context of lipid production at both cell biological (for example, compartmentalization of reactions) and metabolite levels as both are important considerations for engineering and modeling of improved strains.

Project Details

Start Date
2018-02-21
End Date
2018-09-30
Status
Closed

Team

Principal Investigator

Scott Baker
Institution
Environmental Molecular Sciences Laboratory

Team Members

Erin Bredeweg
Institution
Environmental Molecular Sciences Laboratory

Kyle Pomraning
Institution
Pacific Northwest National Laboratory

Young-Mo Kim
Institution
Pacific Northwest National Laboratory

Thomas Metz
Institution
Pacific Northwest National Laboratory

Related Publications

Pomraning K.R., E.L. Bredeweg, E.J. Kerkhoven, K.W. Barry, S. Haridas, H. Hundley, and K.M. LaButti, et al. 2018. "Regulation of yeast-to-hyphae transition in Yarrowia lipolytica." mSphere 3, no. 6:Article No. e00541-18. PNNL-SA-131456. doi:10.1128/mSphere.00541-18