Medical Defenses Against Emerging Infectious Disease
EMSL Project ID
51053
Abstract
Hemorrhagic fever viruses like Ebola, Marburg, and Lassa cause up to 90% lethality. To study these re-emerging threats to human health and develop the needed vaccines and antivirals, our laboratory employs a spectrum of tools, from atomic structure to model virus infection, combining structural biology and biochemistry with cellular virology, immunology, and field studies in Africa. This proposal describes research aimed at understanding what makes an effective antibody response to these viruses, and how the virus assembles and buds from infected cells with the goal of developing better antibodies and antivirals to inhibit virus infection.
Project Details
Start Date
2019-11-11
End Date
2020-08-10
Status
Closed
Released Data Link
Team
Principal Investigator
Co-Investigator(s)
Team Members