Integrative fungal lipidomics map: a tool to visualize lipid metabolism in large omics experiments
EMSL Project ID
51301
Abstract
Fungi have highly versatile lipid metabolisms, making them an excellent platform for developing antifungal therapies and biotechnological products. However, fungal lipid metabolism has been well characterized only in Saccharomyces cerevisiae, which has a very unique profile, limiting the application of this knowledge to important medical or biotechnological settings. A major hurdle for studying fungal lipid metabolism is the lack of tools that can provide a global view of the fungal lipid metabolic map and highlight changes in response to treatments or gene engineering. Our goal in this application is to build a map of fungal lipid metabolism. This map will be user friendly and integrated with omics data to provide a global view of the specific pathways that are regulated with different treatments and gene engineering. This work will provide a tool tying bioinformatic annotation, experimental treatments, and multi-omic measurements that will facilitate the study of the fungal lipid metabolism, which will have an impact with both biomedical and biotechnological research.
Project Details
Start Date
2020-02-12
End Date
2022-09-30
Status
Closed
Released Data Link
Team
Principal Investigator
Co-Investigator(s)
Team Members