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Identifying & Translating OP Receptors in Animal Models and Humans using ABPP


EMSL Project ID
51804

Abstract

This EMSL Resource Owner proposal requests use of EMSL resources, owned or co-owned, in order to successfully accomplish the use of activity based protein profiling (ABPP) capabilities to identify and quantify protein receptors within animal models. The use of ABPPs in this regard is a step towards developing a better understanding of how exposure to organophosphates (OPs) impact GABA receptor and other proteins. This stated objective is part of a research grant recently funded by DTRA (Aaron T. Wright, PI).

Project Details

Start Date
2021-01-25
End Date
2023-09-30
Status
Closed

Team

Principal Investigator

Aaron Wright
Institution
Pacific Northwest National Laboratory

Team Members

Agne Nixon
Institution
Pacific Northwest National Laboratory

Vivian Lin
Institution
Pacific Northwest National Laboratory

Stephen Callister
Institution
Pacific Northwest National Laboratory