Skip to main content

Investigation of 4Fe-4S cluster complexes with peptides as the terminl ligand

EMSL Project ID
6903
Award DOI
https://dx.doi.org/10.46936/cpcy.proj.2006.6903/60007015

Abstract

Fe-S proteins exist in all kinds of organisms and play critical roles as electron transfer agents, catalysts, or O2/Fe sensors. Small molecule analogue complexes have been studied extensively.To get better protein models, we will prepare complexes using peptide as the ligand to simulate the protein environment. We will use the FTICR in 1142/EMSL to do mass spectrometry and surface induced dissociation on the new products.

Project Details

Start Date
2006-02-07
End Date
2006-08-30
Status
Closed
Released Data Link
https://search.emsl.pnnl.gov/?project_id_search=6903

Team

Principal Investigator

You-jun Fu
Institution
Washington State University Tri-Cities

Team Members

Xuebin Wang
Institution
Pacific Northwest National Laboratory

Lai-Sheng Wang
Institution
Brown University

Julia Laskin
Institution
Purdue University

Related Publications

Fu Y, J Laskin, and LS Wang. 2006. "Collision Induced Dissociation of [4Fe-4S] Cubane Cluster Complexes: [Fe4S4C14-x(SC2H5)x]2-/1- (x=0-4)." International Journal of Mass Spectrometry 255-256:102-110.
Y. Fu, J. Laskin, and L.-S. Wang. “Electronic Structure and Fragmentation Properties of [Fe4S4(SEt)4-x(SSEt)x]2-," Int. J. Mass Spectrom., 263, 260–266 (2007).