PNNL/NESG Structural Genomics
EMSL Project ID
7597
Abstract
PNNL is a member of the Northeast Structural Genomics Consortium (NESG), a NIH-funded pilot project intended to explore the feasability of and technical challenges presented by high-throughput structural proteomics. For several years EMSL high field NMR facilities have been used extensively by NESG for protein NMR data collection. This new proposal is intended to replace the time formerly provided as "internal" time to NESG Co-PI Michael Kennedy of PNNL. We estimate that approximately 75% of Dr. Kennedy's internal time was used for data collection for NESG target proteins, and this is the basis for the amount of time being requested. This amount of time should be sufficient for complete data sets to be collected on 2-3 novel NESG targets.
Project Details
Project type
Capability Research
Start Date
2004-12-29
End Date
2006-04-04
Status
Closed
Released Data Link
Team
Principal Investigator
Related Publications
Everett JK, R Tejero, SB Murthy, T Acton, JM Aramini, M Baran, J Benach, JR Cort, A Eletsky, F Forouhar, R Guan, AP Kuzin, HW Lee, G Liu, R Mani, B Mao, JL Mills, AF Montelione, K Pederson, R Powers, TA Ramelot, PM Rossi, J Seetharaman, D Snyder, GVT Swapna, SM Vorobiev, Y Wu, R Xiao, Y Yang, CH Arrowsmith, JF Hunt, MA Kennedy, JH Prestegard, T Szyperski, L Tong, and G Montelione. 2016. "A Community Resource of Experimental Data for NMR / X-ray Crystal Structure Pairs." Protein Science 25(1):30-45. doi:10.1002/pro.2774
Yin C, JM Aramini, LC Ma, JR Cort, GVT Swapna, RM Krug, and G Montelione. 2011. "Backbone and Ile-?1, Leu, Val Methyl 1H, 13C and 15N NMR chemical shift assignments for human interferon-stimulated gene 15 protein." Biomolecular NMR Assignments 5(2):215-219. doi:10.1007/s12104-011-9303-8