Projects

The Secretome of Metal-Reducing Shewanella oneidensis

Lead Institution

Georgia Institute of Technology

Principal Investigator

Thomas DiChristina

Project type

Large-Scale EMSL Research

The metabolic reactions catalyzed by metal- and radionuclide-reducing bacteria greatly influence the geochemistry of natural and contaminated environments. One of the more remarkable activities…

NMR Analysis of Bioprocess Samples

Lead Institution

Washington State University Tri-Cities

Principal Investigator

Kathleen McAteer

Project type

Large-Scale EMSL Research

The overall project is directed towards utilization of filamentous fungi for conversion of complex biomass to industrial commodity chemicals biofuels, organic acids or chemical feed-stocks for other…

ETA-Photovoltaics materials Interface optimization

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Timothy Droubay

Project type

Large-Scale EMSL Research

We will provide a fundamental scientific foundation to understand the charge transport in novel oxide-based solar cells, and to tailor the transport by doping and/or interface modification of the…

Protein dynamics with multiple-structural transitions: Investigation with single-molecule FRET

Lead Institution

Washington State University

Principal Investigator

Wen-Ji Dong

Project type

Large-Scale EMSL Research

Dynamics of protein conformational changes and protein-protein interactions play critical roles in biological systems. In response to a specific signal stimulus, the functions of multi-components…

Thin Film Characterization by Rutherford Backscattering (RBS) as a Strong Complement to Our Current Research Efforts (Science Theme)

Lead Institution

Brigham Young University

Principal Investigator

Matthew Linford

Project type

Large-Scale EMSL Research

In my group at BYU and through my past research we have a great deal of experience in modification of substrates with thin films, including monolayers, polymeric coatings, and sputtered films. We…

Electron Transfer Mechanisms in Biofilms

Lead Institution

Washington State University

Principal Investigator

Haluk Beyenal

Project type

Large-Scale EMSL Research

Although interactions of microorganisms with electrodes have been studied in the literature, the mechanisms of electron transfer are still poorly understood. The goal of this proposal is to…

Immunodominance hierarchies in influenza specific CD8+ T cell responses

Lead Institution

University of Tennessee

Principal Investigator

Heather Smallwood

Project type

Large-Scale EMSL Research

The phenomenon of immunodominance has been observed in B cell, CD4+ T cell and CD8+ T cell antigen-specific responses in virtually all types of infection and in tumor immunity model. It is still…

Adsorption of highly functional oxygenates on metal surfaces

Lead Institution

University of Colorado at Boulder

Principal Investigator

James Medlin

Project type

Large-Scale EMSL Research

This proposal is aimed at conducting computational studies to investigate the surface chemistry of functional alcohols on Pd(111) and related surfaces. Such alcohols are key intermediates in the…

Characterization of Energy Storage Systems Using In Situ and Ex Situ Nuclear Magnetic Resonance Spectroscopy

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Jian-zhi Hu

Project type

Large-Scale EMSL Research

Fundamental research in stationary battery has been limited and an in-situ NMR method to probe transient electrochemical reactions has yet to be developed. We propose to develop unique in situ NMR…

Correlated Structure and Dynamics of Ions and Water at Mineralogical Solid-Water Interfaces

Lead Institution

St. Mary's College of Maryland

Principal Investigator

Geoffrey Bowers

Project type

Large-Scale EMSL Research

The objective of this work is to gain new insight into fundamental processes that occur at solid-fluid interfaces by performing a detailed, molecular-scale study of cation and H2O behavior at…

W-band pulsed EPR: a) probing 17O ligands in the Mo(V) site of sulfite oxidases; b) ascertaining the long distance limit in Pulse Dipolar Spectroscopy of Gd(III) labeled macrobiomolecules.

Lead Institution

University of Arizona

Principal Investigator

John Enemark

Project type

Large-Scale EMSL Research

Abstract W-band pulsed EPR: a) probing 17O ligands in the Mo(V) site of sulfite oxidases; b) ascertaining the long distance limit in Pulse Dipolar Spectroscopy of Gd(III) labeled macrobiomolecules…

Double Heterojunction Organic Hybrid Electrodes and Interfacial Charge Transfer Characterizations Using Novel Optical Spectroscopy Techniques

Lead Institution

University of Alabama

Principal Investigator

Shanlin Pan

Project type

Large-Scale EMSL Research

Hybrid OPVs promise to be efficient and cheap devices to convert solar energy to electricity in comparison with their inorganic and organic counterparts. A hybrid OPV, however, has limited efficiency…

Chemical characterization of organic and biogenic atmospheric aerosol particles and their potential to initiate ice crystal formation

Lead Institution

State University of New York at Stony Brook

Principal Investigator

Daniel Knopf

Project type

Large-Scale EMSL Research

Atmospheric aerosol particles can affect the environment by changing the global radiative budget, increasing air pollution and impacting air quality with subsequent consequences for health related…

Vegetation Influences on Long-Term Carbon Stabilization in Soils: A Continuation of Previous Research

Lead Institution

Lawrence Berkeley National Laboratory

Principal Investigator

Margaret Torn

Project type

Large-Scale EMSL Research

This project is a continuation of our previous research that investigates the influence of vegetation on long-term carbon stabilization in soils using molecular level analysis. Previously, we have…

Critical interface properties of metalorganic species of technological and fundamental importance.

Lead Institution

Washington State University

Principal Investigator

Kerry Hipps

Project type

Large-Scale EMSL Research

This project focuses on in depth fundamental understanding of the interfaces of metalorganic films. As a model for porphyrins, phthalocyanines, and other technologically important metalorganics, we…

Solid state NMR investigations of phosphate sequestration by modified clays and inorganic (oxy) hydroxides

Lead Institution

University of Southern Denmark, Odense

Principal Investigator

Ulla Gro Nielsen

Project type

Large-Scale EMSL Research

Phosphate, which is extensively used as a fertilizer and a detergent additive, is leached into fresh water bodies causing algae bloom and subsequent oxygen deficiency, especially in lakes. Two of the…

Development of a systems-level model of cellular dynamics in response to different environmental conditions in cyanobacteria

Lead Institution

Purdue University

Principal Investigator

Louis Sherman

Project type

Large-Scale EMSL Research

This proposal will utilize a systems biology approach to develop a knowledgebase of the metabolic and regulatory networks that can ultimately be used for the photobiological production of advanced…

Internalization and Fate of Engineered Nanomaterials in Developing Zebrafish Embryos

Lead Institution

Oregon State University

Principal Investigator

Robert Tanguay

Project type

Large-Scale EMSL Research

The growing commerce in micro- and nanotechnology is expected to increase human exposure to submicrometer and nanoscale particles. Adverse effects of these particles on living systems have been…

Cellular Interactions and Fate of Engineered Nanomaterials in Alveolar Epithelial Cells at the Air-Liquid Interface

Lead Institution

Oregon State University

Principal Investigator

Bettye Maddux

Project type

Large-Scale EMSL Research

The growing commerce in micro- and nanotechnology is expected to increase human exposure to submicrometer and nanoscale particles. Adverse effects of these particles on living systems have been…

Nanoparticle design, synthesis and characterization for NIH Center Integrating Structure, Activity, Biokinetics and Response for Engineered Nanoparticle (ENP) Risk Assessment

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Donald Baer

Project type

Large-Scale EMSL Research

This work provides the essential materials science base for designing, synthesizing and delivering three types of nanoparticles for three mechanistic nanotoxicology related biological studies being…