Projects

Surface Chemistry of Nanocrystalline Zeolites Probed by Magnetic Resonance Techniques

Lead Institution

University of Iowa

Principal Investigator

Sarah Larsen

Project type

Large-Scale EMSL Research

Nanocrystalline zeolites (with crystal sizes of less than 50 nm) are versatile, porous nanomaterials with potential applications in a broad range of areas including bifunctional catalysis, drug…

Airborne Measurement of Dimethylsulfide, Isoprene, and other Trace Volatile Organic Compounds using a Proton Transfer Reaction Mass Spectrometer during the 2008 DOE ASP VOCALS Field Campaign

Lead Institution

Brookhaven National Laboratory

Principal Investigator

Yin-Nan Lee

Project type

Large-Scale EMSL Research

This proposal requests the participation of EMSL scientist Dr. M. Lizabeth Alexander as a collaborator to deploy on the DOE G-1 aircraft a state-of-the-art volatile organic compound instrument, the…

Effects of the Presence of Helium on Silicon Carbide (EMSL3043)

Lead Institution

University of Arizona

Principal Investigator

L. Corrales

Project type

Exploratory Research

In collaboration between WJ Weber and LR Corrales of PNNL, and C Meis, A Chartier and RM Van Ginhoven of the CEA/Saclay, a study on the interactions of He with SiC crystal forms will be carried out…

Catalytic Studies of Transition Metal Oxide Monolayers Supported on Metal Single Crystal Surfaces

Lead Institution

Southern Illinois University

Principal Investigator

Qingfeng Ge

Project type

Large-Scale EMSL Research

Current commercial heterogeneous catalysts are structurally and chemically complex and measurements on them can seldom be interpreted with atomic-level precision. This is especially true for…

Integrated top-down and bottom-up proteomics strategy to identify multisite and multistep modifications on radiation sensitive proteins

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

David Stenoien

Project type

Large-Scale EMSL Research

In order for a cell to mount the appropriate response to a stimulus such as radiation, it must have the necessary biosensors capable of assessing inputs from multiple intracellular and extracellular…

Heterogeneous Ice Nucleation from Biomass Burning Particles: The Effect of Chemical
Composition and Chemical Aging

Lead Institution

State University of New York at Stony Brook

Principal Investigator

Daniel Knopf

Project type

Large-Scale EMSL Research

Organic material is ubiquitous in atmospheric particles. This proposal focuses on potential ice nucleation (IN) activity of biomass burning aerosol (BBA). Biomass burning is a major source of gases…

Multidimensional High-Field Magic-Angle Spinning NMR
of Membrane and Nanocrystalline Proteins

Lead Institution

University of Illinois at Urbana-Champaign

Principal Investigator

Chad Rienstra

Project type

Large-Scale EMSL Research

We aim to extend ongoing studies of membrane and fibril protein structure at the University of Illinois, conducted on 500 and 750 MHz instruments in 3.2 mm magic-angle spinning rotors, to the 900 MHz…

Preparation of Novel Catalysts using Ion Soft-Landing

Lead Institution

National Dong Hwa University

Principal Investigator

Wen-Ping Peng

Project type

Large-Scale EMSL Research

Soft landing of low energy gas-phase ion beams onto suitable substrates is a powerful preparative technique with many potential applications. Various classes of compounds (e.g. proteins, metal…

Morphology, Composition and Surface Properties of Novel Functional Multimetallic and Core-shell Nanoparticles and Assemblies

Lead Institution

State University of New York at Binghamton

Principal Investigator

Chuan-Jian Zhong

Project type

Large-Scale EMSL Research

This proposal focuses on the utilization of the EMSL User facilities for the investigation of Morphology, Composition and Surface Properties of Novel Multimetallic Alloy and Core-shell Nanoparticles…

Biogeochemical Processes Responsible for the Enhanced Transport of Plutonium under Transient Unsaturated Condtions.

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Ravi Kukkadapu

Project type

Large-Scale EMSL Research

Plutonium is an element of concern because of its radiotoxicity. At Savannah River Site (SRS), as a result of processing Pu for nuclear weapons, some ~60 Ci of 238Pu and 239Pu was released into…

Identification of Precipitates and Chemistry of Interfaces in Optical Materials

Lead Institution

Washington State University

Principal Investigator

David Bahr

Project type

Large-Scale EMSL Research

This proposal is focused on using EMSLs advanced characterization tools, particularly the recent FIB/SEM instrument, to conclusively identify second phase precipitates and grain boundary adsorbates…

A proteomic analysis of the effects of environmental factors on hydrogen production in the cyanobacterium Anabaena variabilis.

Lead Institution

University of Missouri - St. Louis

Principal Investigator

Teresa Thiel

Project type

Large-Scale EMSL Research

The filamentous cyanobacterium, Anabaena variabilis, produces hydrogen from water, using sunlight as the energy source and carbon dioxide as the carbon source. Hydrogen is made in specialized cells…

The proteome of prostate cancer-derived exosomes: Exosomes as biomarker treasure chests

Lead Institution

Erasmus University Medical Center, Rotterdam

Principal Investigator

Guido Jenster

Project type

Large-Scale EMSL Research

Prostate cancer (PCa) is the most common cancer and the second leading cause of cancer death in men. Although considerable progress in the clinical setting has been made in the past decades, early…

Solid-State NMR Structural Studies of HIV-1 CA Protein Assembly

Lead Institution

University of Delaware

Principal Investigator

Tatyana Polenova

Project type

Large-Scale EMSL Research

This is an application in response to the proposal call "Science Theme: Biological Interactions and Dynamics". We request standard, general non-proprietary access to the 900 MHz solid-state…

Mechanisms of nanocrystalline uraninite oxidation by iron minerals under of sulfate-reducing bacteria

Lead Institution

South Dakota School of Mines and Technology

Principal Investigator

Rajesh Sani

Project type

Large-Scale EMSL Research

Uranium (U) is the most common radionuclide in soils, sediments, and groundwater at many sites including U.S. DOE sites and is therefore of particular environmental concern. Subsurface bacteria such…

Comprehensive Analysis Of Post-Translational Modifications (PTMs) In Proteins Involved In Histone Pre-mRNA Processing By High Performance nanoLC-MS

Lead Institution

University of North Carolina

Principal Investigator

Roopa Thapar

Project type

Large-Scale EMSL Research

All eukaryotic mRNAs undergo a series of posttranscriptional processing events that lead to the generation of a mature mRNA transcript which is then translated. These pre-mRNA processing steps…

Structural basis of the lysis clock in bacteriophages: the holin-antiholin interaction of phage lambda

Lead Institution

Texas A&M University

Principal Investigator

Christian Hilty

Project type

Large-Scale EMSL Research

Bacteria are the most abundant organisms in the biosphere, and, after cell division, the second most common fate of bacterial cells is lysis by bacteriophage. For most bacteriophages, the duration…

Proteomic Analysis of Extracellular Appendages Displayed in Desulfovibrio vulgaris

Lead Institution

Oak Ridge National Laboratory

Principal Investigator

Dwayne Elias

Project type

Large-Scale EMSL Research

Sulfate-reducing bacteria makeup a substantial portion of subsurface microbial communities at DOE contaminated sites in particular. They are capable of reducing and immobilizing, soluble U(VI) by…

Phosphoproteomic profiling of breast cancer cell lines

Lead Institution

Erasmus University Medical Center, Rotterdam

Principal Investigator

Arzu Umar

Project type

Large-Scale EMSL Research

Breast cancer is a very heterogeneous disease, consisting of different molecular subtypes. Effective, targeted treatment is available for estrogen receptor (ER) and human epidermal growth factor…

Abiotic reduction of U(VI) by sorbed Fe(II) and the implications for field-scale bioremediation at the Rifle IFC project site

Lead Institution

US Geological Survey, Menlo Park

Principal Investigator

Kate Campbell

Project type

Large-Scale EMSL Research

Bioremediation of uranium-contaminated sites has recently been explored as a potentially effective groundwater treatment option. The injection of an organic carbon substrate such as acetate…