Instruments and resources information
Super resolution structured illumination and Airyscan fluorescence microscope
The Airyscan module, mounted on the confocal fluorescence microscope, provides 3D imaging with a superior detection sensitivity and speed compared when compared to the standalone structured illumination microscopy system or classic confocal microscope. This capability is available at the Environmental Molecule Sciences Laboratory (EMSL) through the EMSL User Program.
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Cell-Free Expression Pipeline
The Cell-Free Expression (CFE) Pipeline is a versatile protein synthesis platform for structural biology and functional annotation applications. It provides fast access to proteins or heteromeric…
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Confocal, Fluorescence Lifetime Imaging, and Multi-Photon Fluorescence Microscope
The Environmental Molecular Sciences Laboratory (EMSL) offers confocal, fluorescence imaging, and multi-photo fluorescence microscope system for environmental and biological research. These resources are available through EMSL's open calls for proposals.
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Cryogenic Focused Ion Beam-Scanning Electron Microscopy
The cryogenic focused ion beam-scanning electron microscope (cryo-FIB-SEM) is a semi-automated instrument that provides pseudo-three-dimensional imaging of thick samples with ~10-nm resolution or…
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Fluorescence-Activated Cell Sorting
The Fluorescence-Activated Cell Sorter (FACS) allows collection and enrichment of unique populations of cells, or single cells, from a heterogenous culture. Cells can be collected based on size,…
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Laser Capture Dissection Microscope
The Zeiss Laser Capture Dissection Microscope allows for the spatially resolved collection and enrichment of unique populations of cells from a thin section of tissue, biofilm, or monolayer of cells…
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Lattice Light Sheet
The Lattice Light Sheet microscope is a tool for imaging living organisms or cells with up to single molecule resolution. This resource is available at the Environmental Molecular Sciences Laboratory (EMSL), a Department of Energy user facility.
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Nanodroplet Processing in One Pot for Trace Samples (NanoPOTS)
The Environmental Molecular Sciences Laboratory offers a microfluidic sample preparation platform called Nanodroplet Processing in One Pot for Trace Samples, or nanoPOTS, for proteomics profiling of biological samples.
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Super Resolution Fluorescence Microscope
The Environmental Molecular Sciences Laboratory offers super resolution fluorescence microscopy instrumentation for analyzing cell-cell and cell-environment interactions and in-situ cellular processes.
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Soil Incubation
The Soil Incubation Laboratory at the Environmental Molecular Sciences Laboratory offers environmental chambers and incubators for conducting controlled lab studies on soils, sediment, and other environmental samples.
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CellenONE
CellenONE is a single-cell isolation and dispensing platform that is used for transcriptomics and proteomics research. Scientists can access and apply CellenONE to their research by submitting a proposal to an open call at the Environmental Molecular Sciences Laboratory (EMSL).
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NanoLive
The NanoLive 3D Cell Explorer CX-A is a microscopy platform available through the EMSL User Program. This platform is designed for repeat observations over time on bacterial and eukaryotic cells.
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Activity-Based Probes
Activity-based probes are available to researchers through the Environmental Molecular Sciences Laboratory (EMSL) User Program to help gain spatio-temporal understanding of functional proteins in biochemical processes.
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