Instruments and resources information
Cell-Free Expression Pipeline
The Cell-Free Expression (CFE) Pipeline is a versatile protein synthesis platform for structural biology and functional annotation applications. It provides fast access to proteins or heteromeric…
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Coherent Anti-Stokes Raman Scattering and Stimulated Raman
Inverted scanning confocal microscope equipped for chemical and biological imaging. Label-based, label-free, and time-resolved imaging of cellular and subcellular dynamics possible in biosystems…
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Confocal, Fluorescence Lifetime Imaging, and Multi-Photon Fluorescence Microscope
The Environmental Molecular Sciences Laboratory (EMSL) offers confocal, fluorescence imaging, and multi-photo fluorescence microscope system for environmental and biological research. These resources are available through EMSL's open calls for proposals.
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Cryogenic Focused Ion Beam-Scanning Electron Microscopy
The cryogenic focused ion beam-scanning electron microscope (cryo-FIB-SEM) is a semi-automated instrument that provides pseudo-three-dimensional imaging of thick samples with ~10-nm resolution or…
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Cryogenic Transmission Electron Microscopy for Environmental Microbiology
The Cryogenic Transmission Electron Microscopy (TEM) suite supports EMSL’s mission to improve our fundamental understanding of environmental and biological systems through
High-resolution imaging…
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Cryogenic Transmission Electron Microscopy for Structural Biology
The Environmental Molecular Sciences Laboratory (EMSL) is home to the Atomic Resolution Cryogenic Transmission Electron Microscopy suite, which includes high-resolution imaging, morphological studies, and structural determination for research related to environmental and biological systems. These resources are available to EMSL users through open calls for proposals.
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Data Visualization
The Environmental Molecular Sciences Laboratory offers visualization resources to the scientific community through open calls for proposals. The resources are vital in advanced data analytics, simulation, and integration.
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Electron Paramagnetic Resonance
The Environmental Molecular Sciences Laboratory (EMSL) offers electron paramagnetic resonance spectroscopy capabilities through the EMSL User Program.
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Fluorescence-Activated Cell Sorting
The Fluorescence-Activated Cell Sorter (FACS) allows collection and enrichment of unique populations of cells, or single cells, from a heterogenous culture. Cells can be collected based on size,…
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Helium Ion Microscopy
Biological and environmental research often requires high-resolution inspection of surface details, such as soil organic matter (SOM)-mineral interactions, ice nucleation in aerosols, and microbial…
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Intermediate Scale Flow Cells
EMSL builds custom flow cells for pore and intermediate scale experiments to study multiphase flow and transport phenomena in saturated and undersaturated subsurface conditions. For pore scale…
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Isotope Ratio Mass Spectrometry
The Environmental Molecular Sciences Laboratory offers access and use of isotope ratio mass spectrometry resources through the EMSL User Program.
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Laser Capture Dissection Microscope
The Zeiss Laser Capture Dissection Microscope allows for the spatially resolved collection and enrichment of unique populations of cells from a thin section of tissue, biofilm, or monolayer of cells…
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Lattice Light Sheet
The Lattice Light Sheet microscope is a tool for imaging living organisms or cells with up to single molecule resolution. This resource is available at the Environmental Molecular Sciences Laboratory (EMSL), a Department of Energy user facility.
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Mid-Range Scientific Computing
Researchers can submit proposals to access mid-range scientific computing and visualization resources and expertise.
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Liquid State NMR for Metabolomics
The Environmental Molecular Sciences Laboratory (EMSL) offers liquid state nuclear magnetic resonance capabilities for metabolomics research through the EMSL User Program.
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Liquid State NMR for Organic Matter/Complex Mixtures
The Environmental Molecular Sciences Laboratory's liquid state nuclear magnetic resonance capabilities for studying mixtures or pure compounds.
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Liquid State NMR for Structural Biology
Liquid state nuclear magnetic resonance at the Environmental Molecular Sciences Laboratory can be used to investigate nucleic acids, peptides, and heterogeneous cell-wall biopolymers, such as lignin and oligosaccharides.
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Mossbauer Spectroscopy
The Environmental Molecular Sciences Laboratory (EMSL) offers a variety of Mössbauer spectroscopy resources for researchers to use through the EMSL User Program.
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Nanodroplet Processing in One Pot for Trace Samples (NanoPOTS)
The Environmental Molecular Sciences Laboratory offers a microfluidic sample preparation platform called Nanodroplet Processing in One Pot for Trace Samples, or nanoPOTS, for proteomics profiling of biological samples.
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