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James Evans
Chemist

Dr. James Evans is a Chemist with the Structural Biology team. He supports the electron microscopy capabilities and develops new technologies and methods for in situ and dynamic multiscale and multimodal bioimaging. He oversees the operation of the cryo-transmission electron microscope (Krios G3i) with direct electron detector for structural biology applications. He is also integrating two Class IV pulsed lasers with a dual aberration corrected JEOL 2200FS to create a new dynamic transmission electron microscope, or DTEM, in the EMSL Quiet Wing. This unique instrument will enable pump-probe, high-resolution electron microscopy on the nanosecond to microsecond timescales to visualize biological macromolecular dynamics in real-time. 

Research Interests

  • Bioimaging 

  • Protein Structure and Dynamics 

  • Cryo-EM 

  • in situ Transmission Electron Microscopy (TEM) 

  • Dynamic TEM 

Education

  • PhD in Biochemistry and Molecular Biology, University of California, Davis, 2007 

  • Business Development Certificate, Graduate School of Management/Center for Entrepreneurship, University of California, Davis, 2007 

Awards and Recognition

  • Microscopy and Microanalysis Presidential Award (2007) 

  • C4E Business Development Fellowship, University of California, Davis (2006) 

  • Molecular and Cellular Biology Training Grant, National Institutes of Health/University of California Davis (2005-2006) 

 

Publications

2020 

 Bhattarai, A., Z. Cheng, A. G. Joly, I. V. Novikova, J. E. Evans, Z. D. Schultz, M. R. Jones, and P. Z. El-Khoury. 2020. “Tip-Enhanced Raman Nanospectroscopy of Smooth Spherical Gold Nanoparticles.” Journal of Physical Chemistry Letters 11 (5): 1795-1801. doi.org/10.1021/acs.jpclett.0c00217.   

Liu, Y., W. S. Peters, D. R. Froelich, A. H. Howell, S. Mooney, J. E. Evans, H. A. Hellmann, and M. Knoblauch. 2020. “Aspartate Residues in a Forisome-Forming SEO Protein Are Critical for Protein Body Assembly and Ca2+ Responsiveness.” Plant and Cell Physiology. doi.org/10.1093/pcp/pcaa093.   

 Woehl, T. J., T. Moser, J. E. Evans, and F. M. Ross. 2020. “Electron-Beam-Driven Chemical Processes During Liquid Phase Transmission Electron Microscopy.” MRS Bulletin 45 (9): 746-753. doi.org/10.1557/mrs.2020.227.   

2019 

Moser, T. H., T. Shokuhfar, and J. E. Evans. 2019. “Considerations for Imaging Thick, Low Contrast, and Beam Sensitive Samples with Liquid Cell Transmission Electron Microscopy.” Micron 117: 8-15. doi.org/10.1016/j.micron.2018.10.007.   

 Perea, D. E., D. K. Schreiber, M. Wirth, and J. E. Evans. 2019. “Advanced FIB-Based Preparation of Cryogenically-Prepared Specimens for APT Analysis.” Microscopy and Microanalysis 25 (S2): 878-879. doi.org/10.1017/S1431927619005129.   

Teeman, E., C. Shasha, J. E. Evans, and K. M. Krishnan. 2019. “Intracellular Dynamics of Superparamagnetic Iron Oxide Nanoparticles for Magnetic Particle Imaging.” Nanoscale 11 (16): 7771-7780. doi.org/10.1039/c9nr01395d. 

2018 

Casadei, C. M., C. J. Tsai, A. Barty, M. S. Hunter, N. A. Zatsepin, C. Padeste, G. Capitani, W. H. Benner, S. Boutet, S. P. Hau-Riege, C. Kupitz, M. Messerschmidt, J. I. Ogren, T. Pardini, K. J. Rothschild, L. Sala, B. Segelke, G. J. Williams, J. E. Evans, X. D. Li, M. Coleman, B. Pedrini, and M. Frank. 2018. “Resolution Extension by Image Summing in Serial Femtosecond Crystallography of Two-Dimensional Membrane-Protein Crystals.” IUCrJ 5: 103-117. doi.org/10.1107/S2052252517017043.   

Gallagher-Jones, M., C. Glynn, D. R. Boyer, M. W. Martynowycz, E. Hernandez, J. Miao, C. T. Zee, I. V. Novikova, L. Goldschmidt, H. T. McFarlane, G. F. Helguera, J. E. Evans, M. R. Sawaya, D. Cascio, D. S. Eisenberg, T. Gonen, and J. A. Rodriguez. 2018. “Sub-ångström Cryo-EM Structure of a Prion Protofibril Reveals a Polar Clasp.” Nature Structural and Molecular Biology 25 (2): 131-134. doi.org/10.1038/s41594-017-0018-0.   

Henske, J. K., S. E. Wilken, K. V. Solomon, C. R. Smallwood, V. Shutthanandan, J. E. Evans, M. K. Theodorou, and M. A. O'Malley. 2018. “Metabolic Characterization of Anaerobic Fungi Provides a Path Forward for Bioprocessing of Crude Lignocellulose.” Biotechnology and Bioengineering 115 (4): 874-884. doi.org/10.1002/bit.26515.   

Moser, T. H., H. Mehta, C. Park, R. T. Kelly, T. Shokuhfar, and J. E. Evans. 2018. “The Role of Electron Irradiation History in Liquid Cell Transmission Electron Microscopy.” Science Advances 4 (4). doi.org/10.1126/sciadv.aaq1202.   

Novikova, I. V., N. Sharma, T. Moser, R. Sontag, Y. Liu, M. J. Collazo, D. Cascio, T. Shokuhfar, H. Hellmann, M. Knoblauch, and J. E. Evans. 2018. “Protein Structural Biology Using Cell-Free Platform from Wheat Germ.” Advanced Structural and Chemical Imaging 4 (1). doi.org/10.1186/s40679-018-0062-9.   

O'Callahan, B. T., K. T. Crampton, I. V. Novikova, T. Jian, C. L. Chen, J. E. Evans, M. B. Raschke, P. Z. El-Khoury, and A. S. Lea. 2018. “Imaging Nanoscale Heterogeneity in Ultrathin Biomimetic and Biological Crystals.” Journal of Physical Chemistry C. doi.org/10.1021/acs.jpcc.8b06681.   

Proetto, M. T., C. E. Callmann, J. Cliff, C. J. Szymanski, D. Hu, S. B. Howell, J. E. Evans, G. Orr, and N. C. Gianneschi. 2018. “Tumor Retention of Enzyme-Responsive Pt(II) Drug-Loaded Nanoparticles Imaged by Nanoscale Secondary Ion Mass Spectrometry and Fluorescence Microscopy.” ACS Central Science 4 (11): 1477-1484. doi.org/10.1021/acscentsci.8b00444.   

Schreiber, D. K., D. E. Perea, J. V. Ryan, J. E. Evans, and J. D. Vienna. 2018. “A Method for Site-Specific and Cryogenic Specimen Fabrication of Liquid/Solid Interfaces for Atom Probe Tomography.” Ultramicroscopy 194: 89-99. doi.org/10.1016/j.ultramic.2018.07.010.   

Sikaroudi, A. E., D. A. Welch, T. J. Woehl, R. Faller, J. E. Evans, N. D. Browning, and C. Park. 2018. “Directional Statistics of Preferential Orientations of Two Shapes in Their Aggregate and Its Application to Nanoparticle Aggregation.” Technometrics 60 (3): 332-344. doi.org/10.1080/00401706.2017.1366949.   

2017 

Abellan, P., T. H. Moser, I. T. Lucas, J. W. Grate, J. E. Evans, and N. D. Browning. 2017. “The Formation of Cerium(III) Hydroxide Nanoparticles by a Radiation Mediated Increase in Local pH.” RSC Advances 7 (7): 3831-3837. doi.org/10.1039/C6RA27066B.  

Geng, T., C. R. Smallwood, E. L. Bredeweg, K. R. Pomraning, A. E. Plymale, S. E. Baker, J. E. Evans, and R. T. Kelly. 2017. “Multimodal Microfluidic Platform for Controlled Culture and Analysis of Unicellular Organisms.” Biomicrofluidics 11 (5). doi.org/10.1063/1.4986533.   

Henske, J. K., S. P. Gilmore, D. Knop, F. J. Cunningham, J. A. Sexton, C. R. Smallwood, V. Shutthanandan, J. E. Evans, M. K. Theodorou, and M. A. O'Malley. 2017. “Transcriptomic Characterization of Caecomyces churrovis: A Novel, Non-Rhizoid-Forming Lignocellulolytic Anaerobic Fungus.” Biotechnology for Biofuels 10 (1). doi.org/10.1186/s13068-017-0997-4.   

Kruska, K., A. Rohatgi, R. S. Vemuri, L. Kovarik, T. H. Moser, J. E. Evans, and N. D. Browning. 2017. “Grain Growth in Nanocrystalline Mg-Al Thin Films.” Metallurgical and Materials Transactions A: Physical Metallurgy and Materials Science 48 (12): 6118-6125. doi.org/10.1007/s11661-017-4350-0.  

Novikova, I. V., C. R. Smallwood, Y. Gong, D. Hu, L. Hendricks, J. E. Evans, A. Bhattarai, W. P. Hess, and P. Z. El-Khoury. 2017. “Multimodal Hyperspectral Optical Microscopy.” Chemical Physics 498-499: 25-32. doi.org/10.1016/j.chemphys.2017.08.011.   

Perea, D. E., S. S. A. Gerstl, J. Chin, B. Hirschi, and J. E. Evans. 2017. “An Environmental Transfer Hub for Multimodal Atom Probe Tomography.” Advanced Structural and Chemical Imaging 3 (1). doi.org/10.1186/s40679-017-0045-2.   

Yu, X., J. Yu, Y. Zhou, Y. Zhang, J. Wang, J. E. Evans, X. Y. Yu, X. L. Wang, and Z. Zhu. 2017. “An Investigation of the Beam Damage Effect on in Situ Liquid Secondary Ion Mass Spectrometry Analysis.” Rapid Communications in Mass Spectrometry 31 (23): 2035-2042. doi.org/10.1002/rcm.7983.   

2016  

Abellan, P., L. R. Parent, N. Al Hasan, C. Park, I. Arslan, A. M. Karim, J. E. Evans, and N. D. Browning. 2016. “Gaining Control over Radiolytic Synthesis of Uniform Sub-3-Nanometer Palladium Nanoparticles: Use of Aromatic Liquids in the Electron Microscope.” Langmuir 32 (6): 1468-1477. doi.org/10.1021/acs.langmuir.5b04200.   

El-Khoury, P. Z., P. Abellan, R. L. Chantry, Y. Gong, A. G. Joly, I. V. Novikova, J. E. Evans, E. Aprà, D. Hu, Q. M. Ramasse, and W. P. Hess. 2016. “The Information Content in Single-Molecule Raman Nanoscopy.” Advances in Physics: X 1 (1): 35-54. doi.org/10.1080/23746149.2016.1140010.   

Evans, J. E., and H. Friedrich. 2016. “Advanced Tomography Techniques for Inorganic, Organic, and Biological Materials.” MRS Bulletin 41 (7): 516-521. doi.org/10.1557/mrs.2016.134.  

Hua, X., C. Szymanski, Z. Wang, Y. Zhou, X. Ma, J. Yu, J. Evans, G. Orr, S. Liu, Z. Zhu, and X. Y. Yu. 2016. “Chemical Imaging of Molecular Changes in a Hydrated Single Cell by Dynamic Secondary Ion Mass Spectrometry and Super-Resolution Microscopy.” Integrative Biology (United Kingdom) 8 (5): 635-644. doi.org/10.1039/c5ib00308c.   

Patterson, J. P., D. B. Collins, J. M. Michaud, J. L. Axson, C. M. Sultana, T. Moser, A. C. Dommer, J. Conner, V. H. Grassian, M. D. Stokes, G. B. Deane, J. E. Evans, M. D. Burkart, K. A. Prather, and N. C. Gianneschi. 2016. “Sea Spray Aerosol Structure and Composition Using Cryogenic Transmission Electron Microscopy.” ACS Central Science 2 (1): 40-47. doi.org/10.1021/acscentsci.5b00344.   

Patterson, J. P., L. R. Parent, J. Cantlon, H. Eickhoff, G. Bared, J. E. Evans, and N. C. Gianneschi. 2016. “Picoliter Drop-on-Demand Dispensing for Multiplex Liquid Cell Transmission Electron Microscopy.” Microscopy and Microanalysis 22 (3): 507-514. doi.org/10.1017/S1431927616000659.   

Perea, D. E., J. Liu, J. Bartrand, Q. Dicken, S. T. Thevuthasan, N. D. Browning, and J. E. Evans. 2016. “Atom Probe Tomographic Mapping Directly Reveals the Atomic Distribution of Phosphorus in Resin Embedded Ferritin.” Scientific Reports 6. doi.org/10.1038/srep22321.  

Proetto, M. T., C. R. Anderton, D. Hu, C. J. Szymanski, Z. Zhu, J. P. Patterson, J. K. Kammeyer, L. G. Nilewski, A. M. Rush, N. C. Bell, J. E. Evans, G. Orr, S. B. Howell, and N. C. Gianneschi. 2016. “Cellular Delivery of Nanoparticles Revealed with Combined Optical and Isotopic Nanoscopy.” ACS Nano 10 (4): 4046-4054. doi.org/10.1021/acsnano.5b06477. 

Welch, D. A., T. J. Woehl, C. Park, R. Faller, J. E. Evans, and N. D. Browning. 2016. “Understanding the Role of Solvation Forces on the Preferential Attachment of Nanoparticles in Liquid.” ACS Nano 10 (1): 181-187. doi.org/10.1021/acsnano.5b06632.   

Zhou, Y., J. Yao, Y. Ding, J. Yu, X. Hua, J. E. Evans, X. Yu, D. B. Lao, D. J. Heldebrant, S. K. Nune, B. Cao, M. E. Bowden, X. Y. Yu, X. L. Wang, and Z. Zhu. 2016. “Improving the Molecular Ion Signal Intensity for in Situ Liquid SIMS Analysis.” Journal of the American Society for Mass Spectrometry 27 (12): 2006-2013. doi.org/10.1007/s13361-016-1478-x.   

2015 

El-Khoury, P. Z., Y. Gong, P. Abellan, B. W. Arey, A. G. Joly, D. Hu, J. E. Evans, N. D. Browning, and W. P. Hess. 2015. “Tip-Enhanced Raman Nanographs: Mapping Topography and Local Electric Fields.” Nano Letters 15 (4): 2385-2390. doi.org/10.1021/acs.nanolett.5b00609.   

El-Khoury, P. Z., G. E. Johnson, I. V. Novikova, Y. Gong, A. G. Joly, J. E. Evans, M. Zamkov, J. Laskin, and W. P. Hess. 2015. “Enhanced Raman Scattering from Aromatic Dithiols Electrosprayed into Plasmonic Nanojunctions.” Faraday Discussions 184: 339-357. doi.org/10.1039/c5fd00036j.   

Feld, G. K., M. Heymann, W. H. Benner, T. Pardini, C. J. Tsai, S. Boutet, M. A. Coleman, M. S. Hunter, X. Li, M. Messerschmidt, A. Opathalage, B. Pedrini, G. J. Williams, B. A. Krantz, S. Fraden, S. Hau-Riege, J. E. Evans, B. W. Segelke, and M. Frank. 2015. “Low-Z Polymer Sample Supports for Fixed-Target Serial Femtosecond X-Ray Crystallography.” Journal of Applied Crystallography 48: 1072-1079. doi.org/10.1107/S1600576715010493.   

Geng, T., E. L. Bredeweg, C. J. Szymanski, B. Liu, S. E. Baker, G. Orr, J. E. Evans, and R. T. Kelly. 2015. “Compartmentalized Microchannel Array for High-Throughput Analysis of Single Cell Polarized Growth and Dynamics.” Scientific Reports 5. doi.org/10.1038/srep16111.   

Li, X., M. Xue, O. G. Raabe, H. L. Aaron, E. A. Eisen, J. E. Evans, F. A. Hayes, S. Inaga, A. Tagmount, M. Takeuchi, C. Vulpe, J. I. Zink, S. H. Risbud, and K. E. Pinkerton. 2015. “Aerosol Droplet Delivery of Mesoporous Silica Nanoparticles: A Strategy for Respiratory-Based Therapeutics.” Nanomedicine: Nanotechnology, Biology, and Medicine 11 (6): 1377-1385. doi.org/10.1016/j.nano.2015.03.007.   

Mehdi, B. L., J. Qian, E. Nasybulin, C. Park, D. A. Welch, R. Faller, H. Mehta, W. A. Henderson, W. Xu, C. M. Wang, J. E. Evans, J. Liu, J. G. Zhang, K. T. Mueller, and N. D. Browning. 2015. “Observation and Quantification of Nanoscale Processes in Lithium Batteries by Operando Electrochemical (S)TEM.” Nano Letters 15 (3): 2168-2173. doi.org/10.1021/acs.nanolett.5b00175.  

Park, C., T. J. Woehl, J. E. Evans, and N. D. Browning. 2015. “Minimum Cost Multi-Way Data Association for Optimizing Multitarget Tracking of Interacting Objects.” IEEE Transactions on Pattern Analysis and Machine Intelligence 37 (3): 611-624. doi.org/10.1109/TPAMI.2014.2346202.   

Patterson, J. P., P. Abellan, M. S. Denny, C. Park, N. D. Browning, S. M. Cohen, J. E. Evans, and N. C. Gianneschi. 2015. “Observing the Growth of Metal-Organic Frameworks by in Situ Liquid Cell Transmission Electron Microscopy.” Journal of the American Chemical Society 137 (23): 7322-7328. doi.org/10.1021/jacs.5b00817.  

Welch, D. A., B. L. Mehdi, H. J. Hatchell, R. Faller, J. E. Evans, and N. D. Browning. 2015. “Using Molecular Dynamics to Quantify the Electrical Double Layer and Examine the Potential for Its Direct Observation in the in-situ TEM.” Advanced Structural and Chemical Imaging 1 (1). doi.org/10.1186/s40679-014-0002-2.   

 2014 

Abellan, P., B. L. Mehdi, L. R. Parent, M. Gu, C. Park, W. Xu, Y. Zhang, I. Arslan, J. G. Zhang, C. M. Wang, J. E. Evans, and N. D. Browning. 2014. “Probing the Degradation Mechanisms in Electrolyte Solutions for Li-Ion Batteries by in Situ Transmission Electron Microscopy.” Nano Letters 14 (3): 1293-1299. doi.org/10.1021/nl404271k.   

Abellan, P., T. J. Woehl, L. R. Parent, N. D. Browning, J. E. Evans, and I. Arslan. 2014. “Factors Influencing Quantitative Liquid (Scanning) Transmission Electron Microscopy.” Chemical Communications 50 (38): 4873-4880. doi.org/10.1039/c3cc48479c.   

Abellan, P., T. J. Woehl, R. G. Tonkyn, W. Andreas Schroeder, J. E. Evans, and N. D. Browning. 2014. “Implementing in situ Experiments in Liquids in the (Scanning) Transmission Electron Microscope ((S)TEM) and Dynamic TEM (DTEM).” Microscopy & Microanalysis. 20 (3): 1648-1649. doi.org/10.1017/S1431927614009970.   

El-Khoury, P. Z., E. Khon, Y. Gong, A. G. Joly, P. Abellan, J. E. Evans, N. D. Browning, D. Hu, M. Zamkov, and W. P. Hess. 2014. “Electric Field Enhancement in a Self-Assembled 2D Array of Silver Nanospheres.” Journal of Chemical Physics 141 (21). doi.org/10.1063/1.4902905.   

Evans, K. A., A. G. Tomkins, J. Cliff, and M. L. Fiorentini. 2014. “Insights into Subduction Zone Sulfur Recycling from Isotopic Analysis of Eclogite-Hosted Sulfides.” Chemical Geology 365: 1-19. doi.org/10.1016/j.chemgeo.2013.11.026.   

Frank, M., D. B. Carlson, M. S. Hunter, G. J. Williams, M. Messerschmidt, N. A. Zatsepin, A. Barty, W. H. Benner, K. Chu, A. T. Graf, S. P. Hau-Riege, R. A. Kirian, C. Padeste, T. Pardini, B. Pedrini, B. Segelke, M. M. Seibert, J. C. H. Spence, C. J. Tsai, S. M. Lane, X. D. Li, G. Schertler, S. Boutet, M. Coleman, and J. E. Evans. 2014. “Femtosecond X-Ray Diffraction from Two-Dimensional Protein Crystals.” IUCrJ 1: 95-100. doi.org/10.1107/S2052252514001444.   

Giacometti, F., K. A. Evans, G. Rebay, J. Cliff, A. G. Tomkins, P. Rossetti, G. Vaggelli, and D. T. Adams. 2014. “Sulfur Isotope Evolution in Sulfide Ores from Western Alps: Assessing the Influence of Subduction-Related Metamorphism.” Geochemistry, Geophysics, Geosystems 15 (10): 3808-3829. doi.org/10.1002/2014GC005459.   

Hunter, M. S., B. Segelke, M. Messerschmidt, G. J. Williams, N. A. Zatsepin, A. Barty, W. Henry Benner, D. B. Carlson, M. Coleman, A. Graf, S. P. Hau-Riege, T. Pardini, M. Marvin Seibert, J. Evans, S. Boutet, and M. Frank. 2014. “Fixed-Target Protein Serial Microcrystallography with an X-Ray Free Electron Laser.” Scientific Reports 4. doi.org/10.1038/srep06026.   

Mehdi, B. L., M. Gu, L. R. Parent, W. Xu, E. N. Nasybulin, X. Chen, R. R. Unocic, P. Xu, D. A. Welch, P. Abellan, J. G. Zhang, J. Liu, C. M. Wang, I. Arslan, J. Evans, and N. D. Browning. 2014. “In-Situ Electrochemical Transmission Electron Microscopy for Battery Research.” Microscopy and Microanalysis 20 (2): 484-492. doi.org/10.1017/S1431927614000488.   

Parent, L. R., D. B. Robinson, P. J. Cappillino, P. Abellan, J. E. Evans, N. D. Browning, and I. Arslan. 2014. “In Situ Observation of Directed Nanoparticle Aggregation During the Synthesis of Ordered Nanoporous Metal in Soft Templates.” Microscopy & Microanalysis. 20 (3): 1600-1601. doi.org/10.1017/S1431927614009738.   

Parent, L. R., D. B. Robinson, P. J. Cappillino, R. J. Hartnett, P. Abellan, J. E. Evans, N. D. Browning, and I. Arslan. 2014. “In Situ Observation of Directed Nanoparticle Aggregation During the Synthesis of Ordered Nanoporous Metal in Soft Templates.” Chemistry of Materials 26 (3): 1426-1433. doi.org/10.1021/cm4035209.   

Patterson, J. P., P. Abellan Baeza, M. Denny, S. Cohen, C. Park, N. D. Browning, J. E. Evans, and N. C. Gianneschi. 2014. “In-Situ Liquid Transmission Electron Microscopy (TEM) for the Analysis of Metal Organic Frameworks (Mofs).” Microscopy & Microanalysis. 20 (3): 1614-1615. doi.org/10.1017/S1431927614009805.   

Pedrini, B., C. J. Tsai, G. Capitani, C. Padeste, M. S. Hunter, N. A. Zatsepin, A. Barty, W. Henry Benner, S. Boutet, G. K. Feld, S. P. Hau-Riege, R. A. Kirian, C. Kupitz, M. Messerschmitt, J. I. Ogren, T. Pardini, B. Segelke, G. J. Williams, J. C. H. Spence, R. Abela, M. Coleman, J. E. Evans, G. F. X. Schertler, M. Frank, and X. D. Li. 2014. “7 Å Resolution in Protein Two-Dimensional-Crystal X-Ray Diffraction at Linac Coherent Light Source.” Philosophical Transactions of the Royal Society B: Biological Sciences 369 (1647). doi.org/10.1098/rstb.2013.0500.   

Proetto, M. T., A. M. Rush, M. P. Chien, P. Abellan Baeza, J. P. Patterson, M. P. Thompson, N. H. Olson, C. E. Moore, A. L. Rheingold, C. Andolina, J. Millstone, S. B. Howell, N. D. Browning, J. E. Evans, and N. C. Gianneschi. 2014. “Dynamics of Soft Nanomaterials Captured by Transmission Electron Microscopy in Liquid Water.” Journal of the American Chemical Society 136 (4): 1162-1165. doi.org/10.1021/ja408513m.   

Silva, R. M., K. Doudrick, L. M. Franzi, C. Teesy, D. S. Anderson, Z. Wu, S. Mitra, V. Vu, G. Dutrow, J. E. Evans, P. Westerhoff, L. S. Van Winkle, O. G. Raabe, and K. E. Pinkerton. 2014. “Instillation Versus Inhalation of Multiwalled Carbon Nanotubes: Exposure-Related Health Effects, Clearance, and the Role of Particle Characteristics.” ACS Nano 8 (9): 8911-8931. doi.org/10.1021/nn503887r.   

Wang, Y. C., D. K. Schreiber, J. J. Neeway, S. Thevuthasan, J. E. Evans, J. V. Ryan, Z. Zhua, and W. D. Wei. 2014. “NanoSIMS Imaging Alteration Layers of a Leached SON68 Glass Via a FIB-Made Wedged Crater.” Surface and Interface Analysis 46 (S1): 233-237. doi.org/10.1002/sia.5585.   

Woehl, T. J., C. Park, J. E. Evans, I. Arslan, W. D. Ristenpart, and N. D. Browning. 2014. “Direct Observation of Aggregative Nanoparticle Growth: Kinetic Modeling of the Size Distribution and Growth Rate.” Nano Letters 14 (1): 373-378. doi.org/10.1021/nl4043328.   

2013  

Acar, S., D. B. Carlson, M. S. Budamagunta, V. Yarov-Yarovoy, J. J. Correia, M. R. Niñonuevo, W. Jia, L. Tao, J. A. Leary, J. C. Voss, J. E. Evans, and J. M. Scholey. 2013. “The Bipolar Assembly Domain of the Mitotic Motor Kinesin-5.” Nature Communications 4. doi.org/10.1038/ncomms2348.   

Carlson, D. B., J. Gelb, V. Palshin, and J. E. Evans. 2013. “Laboratory-Based Cryogenic Soft X-Ray Tomography with Correlative Cryo-Light and Electron Microscopy.” Microscopy and Microanalysis 19 (1): 22-29. doi.org/10.1017/S1431927612013827.   

Evans, J. E., P. Blackborow, S. J. Horne, and J. Gelb. 2013. “Whole Cell Tomography/Molecular Biology/Structural Biology: Affordable X-Ray Microscopy with Nanoscale Resolution.” BioOptics World 6 (2): 28-39.  

Evans, J. E., and N. D. Browning. 2013. “Enabling Direct Nanoscale Observations of Biological Reactions with Dynamic TEM.” Journal of Electron Microscopy 62 (1): 147-156. doi.org/10.1093/jmicro/dfs081.   

Gu, M., L. R. Parent, B. L. Mehdi, R. R. Unocic, M. T. McDowell, R. L. Sacci, W. Xu, J. G. Connell, P. Xu, P. Abellan, X. Chen, Y. Zhang, D. E. Perea, J. E. Evans, L. J. Lauhon, J. G. Zhang, J. Liu, N. D. Browning, Y. Cui, I. Arslan, and C. M. Wang. 2013. “Demonstration of an Electrochemical Liquid Cell for Operando Transmission Electron Microscopy Observation of the Lithiation/Delithiation Behavior of Si Nanowire Battery Anodes.” Nano Letters 13 (12): 6106-6112. doi.org/10.1021/nl403402q.   

Lu, Y. J., R. Kerrich, A. I. S. Kemp, T. C. McCuaig, Z. Q. Hou, C. J. R. Hart, Z. X. Li, P. A. Cawood, L. Bagas, Z. M. Yang, J. Cliff, E. A. Belousova, F. Jourdan, and N. J. Evans. 2013. “Intracontinental Eocene-Oligocene Porphyry Cu Mineral Systems of Yunnan, Western Yangtze Craton, China: Compositional Characteristics, Sources, and Implications for Continental Collision Metallogeny.” Economic Geology 108 (7): 1541-1576. doi.org/10.2113/econgeo.108.7.1541.   

Mehraeen, S., J. T. McKeown, P. V. Deshmukh, J. E. Evans, P. Abellan, P. Xu, B. W. Reed, M. L. Taheri, P. E. Fischione, and N. D. Browning. 2013. “A (S)TEM Gas Cell Holder with Localized Laser Heating for in Situ Experiments.” Microscopy and Microanalysis 19 (2): 470-478. doi.org/10.1017/S1431927612014419.   

Mortensen, D. R., G. T. Seidler, J. A. Bradley, M. J. Lipp, W. J. Evans, P. Chow, Y. M. Xiao, G. Boman, and M. E. Bowden. 2013. “A Versatile Medium-Resolution X-Ray Emission Spectrometer for Diamond Anvil Cell Applications.” Review of Scientific Instruments 84 (8). doi.org/10.1063/1.4819257.   

Silva, R. M., C. Teesy, L. Franzi, A. Weir, P. Westerhoff, J. E. Evans, and K. E. Pinkerton. 2013. “Biological Response to Nano-Scale Titanium Dioxide (TiO2): Role of Particle Dose, Shape, and Retention.” Journal of Toxicology and Environmental Health - Part A: Current Issues 76 (16): 953-972. doi.org/10.1080/15287394.2013.826567.   

Welch, D. A., R. Faller, J. E. Evans, and N. D. Browning. 2013. “Simulating Realistic Imaging Conditions for in Situ Liquid Microscopy.” Ultramicroscopy 135: 36-42. doi.org/10.1016/j.ultramic.2013.05.010.   

Woehl, T. J., K. L. Jungjohann, J. E. Evans, I. Arslan, W. D. Ristenpart, and N. D. Browning. 2013. “Experimental Procedures to Mitigate Electron Beam Induced Artifacts During in Situ Fluid Imaging of Nanomaterials.” Ultramicroscopy 127: 53-63. doi.org/10.1016/j.ultramic.2012.07.018.   

2012  

Abellán, P., J. T. McKeown, S. Mehraeen, P. Xu, P. V. Deshmukh, J. Evans, and N. D. Browning. 2012. “High Gas Pressure/High Temperature in Situ Investigation of Nanomaterials by STEM-EELS.” Microscopy and Microanalysis 18 (S2): 1170-1171. doi.org/10.1017/S1431927612007702.   

Benner, W. H., G. S. Lewis, S. V. Hering, B. Selgelke, M. Corzett, J. E. Evans, and F. C. Lightstone. 2012. “Re-Electrospraying Splash-Landed Proteins and Nanoparticles.” Analytical Chemistry 84 (5): 2498-2504. doi.org/10.1021/ac203298w.   

Browning, N. D., M. A. Bonds, G. H. Campbell, J. E. Evans, T. Lagrange, K. L. Jungjohann, D. J. Masiel, J. McKeown, S. Mehraeen, B. W. Reed, and M. Santala. 2012. “Recent Developments in Dynamic Transmission Electron Microscopy.” Current Opinion in Solid State and Materials Science 16 (1): 23-30. doi.org/10.1016/j.cossms.2011.07.001.   

Carlson, D. B., J. Gelb, V. Palshin, and J. E. Evans. 2012. “Laboratory Cryogenic Soft X-Ray Tomography and Correlative Microscopy: 3d Visualization inside the Cell.” Microscopy and Microanalysis 18 (S2): 838-839. doi.org/10.1017/S1431927612006046.   

Evans, J. E., I. Arslan, K. L. Jungjohann, T. J. Woehl, and N. D. Browning. 2012. “In Situ Liquid Stem for Observing the Interface between Biology and Nanotechnology.” Microscopy and Microanalysis 18 (S2): 1130-1131. doi.org/10.1017/S1431927612007507.   

Evans, J. E., K. L. Jungjohann, P. C. K. Wong, P. L. Chiu, G. H. Dutrow, I. Arslan, and N. D. Browning. 2012. “Visualizing Macromolecular Complexes with in Situ Liquid Scanning Transmission Electron Microscopy.” Micron 43 (11): 1085-1090. doi.org/10.1016/j.micron.2012.01.018.  

Guglielmino, K., K. Jackson, T. R. Harris, V. Vu, H. Dong, G. Dutrow, J. E. Evans, J. Graham, B. P. Cummings, P. J. Havel, N. Chiamvimonvat, S. Despa, B. D. Hammock, and F. Despa. 2012. “Pharmacological Inhibition of Soluble Epoxide Hydrolase Provides Cardioprotection in Hyperglycemic Rats.” American Journal of Physiology-Heart and Circulatory Physiology 303 (7): H853-H862. doi.org/10.1152/ajpheart.00154.2012.   

Jungjohann, K. L., J. E. Evans, J. A. Aguiar, I. Arslan, and N. D. Browning. 2012. “Atomic-Scale Imaging and Spectroscopy for in Situ Liquid Scanning Transmission Electron Microscopy.” Microscopy and Microanalysis 18 (3): 621-627. doi.org/10.1017/S1431927612000104.   

Jungjohann, K. L., J. E. Evans, I. Arslan, and N. D. Browning. 2012. “Analysis of Imaging Conditions for Liquid Cell S/TEM.” Microscopy and Microanalysis 18: 1150-1151. doi.org/10.1017/S143192761200760X.   

Madl, A. K., S. V. Teague, Y. Qu, D. Masiel, J. E. Evans, T. Guo, and K. E. Pinkerton. 2012. “Aerosolization System for Experimental Inhalation Studies of Carbon-Based Nanomaterials.” Aerosol Science and Technology 46 (1): 94-107. doi.org/10.1080/02786826.2011.605813.   

Mehraeen, S., J. T. McKeown, P. V. Deshmukh, J. E. Evans, B. W. Reed, and N. D. Browning. 2012. “Toward Atomic Resolution Stem Imaging at Atmospheric Pressure.” Microscopy and Microanalysis 18 (S2): 1172-1173. doi.org/10.1017/S1431927612007714.   

Parent, L. R., D. B. Robinson, P. J. Cappillino, J. E. Evans, N. D. Browning, and I. Arslan. 2012. “Towards Optimizing Synthesis of Metallic Nanostructures in Soft Templates Using in-Situ Liquid Stage Microscopy.” Microscopy and Microanalysis 18 (S2): 1088-1089. doi.org/10.1017/S1431927612007295.   

Parent, L. R., D. B. Robinson, T. J. Woehl, W. D. Ristenpart, J. E. Evans, N. D. Browning, and I. Arslan. 2012. “Direct in Situ Observation of Nanoparticle Synthesis in a Liquid Crystal Surfactant Template.” ACS Nano 6 (4): 3589-3596. doi.org/10.1021/nn300671g.   

Schwartz, E. K., W. D. Wright, K. T. Ehmsen, J. E. Evans, H. Stahlberg, and W. D. Heyer. 2012. “Mus81-Mms4 Functions as a Single Heterodimer to Cleave Nicked Intermediates in Recombinational DNA Repair.” Molecular and Cellular Biology 32 (15): 3065-3080. doi.org/10.1128/MCB.00547-12.   

Woehl, T. J., J. E. Evans, I. Arslan, W. D. Ristenpart, and N. D. Browning. 2012. “Direct in Situ Determination of the Mechanisms Controlling Nanoparticle Nucleation and Growth.” ACS Nano 6 (10): 8599-8610. doi.org/10.1021/nn303371y.   

Woehl, T. J., J. E. Evans, I. Arslan, W. D. Ristenpart, and N. D. Browning. 2012. “The Effect of Electron Dose on Beam Induced Silver Nanocrystal Growth Kinetics and Morphology.” Microscopy and Microanalysis 18: 1100-1101. doi.org/10.1017/S1431927612007350.   

2011 

Carlson, D. B., and J. E. Evans. 2011. “Low-Cost Cryo-Light Microscopy Stage Fabrication for Correlated Light/Electron Microscopy.” Journal of Visualized Experiments (52). doi.org/10.3791/2909.   

Chu, K., J. Evans, N. Rohringer, S. Hau-Riege, A. Graf, M. Frank, Z. J. Smith, and S. Lane. 2011. “In-Plane Rotation Classification for Coherent X-Ray Imaging of Single Biomolecules.” Optics Express 19 (12): 11691-11704. doi.org/10.1364/OE.19.011691.   

Evans, J. E., K. L. Jungjohann, N. D. Browning, and I. Arslan. 2011. “Controlled Growth of Nanoparticles from Solution with in Situ Liquid Transmission Electron Microscopy.” Nano Letters 11 (7): 2809-2813. doi.org/10.1021/nl201166k.   

Mabuchi, Y., T. Nakajima, K. Chaudhuri, J. E. Evans, N. D. Browning, and S. Okamura. 2011. “Investigation on Thickness Effect of Ultrathin Vinylidene Fluoride/Trifluoroethylene Copolymer Films.” Japanese Journal of Applied Physics 50 (9 PART 3). doi.org/10.1143/JJAP.50.09NA05.   

2010 

Browning, N. D., G. H. Campbell, J. E. Evans, T. B. LaGrange, and B. W. Reed. 2010. “Electron Microscopy and Spectroscopy on the Ultrafast Timescale.” ChemPhysChem 11 (4): 781-782. doi.org/10.1002/cphc.200900937.   

Taheri, M. L., S. McGowan, L. Nikolova, J. E. Evans, N. Teslich, J. P. Lu, T. Lagrange, F. Rosei, B. J. Siwick, and N. D. Browning. 2010. “In Situ Laser Crystallization of Amorphous Silicon: Controlled Nanosecond Studies in the Dynamic Transmission Electron Microscope.” Applied Physics Letters 97 (3). doi.org/10.1063/1.3422473.   

2009 

Evans, J. E., I. Arslan, D. L. Jaeger, E. A. Marquis, B. P. Gorman, and N. D. Browning. 2009. “3-D Atom Probe Tomography of Resin Embedded Samples?” Microscopy and Microanalysis 15 (SUPPL. 2): 274-275. doi.org/10.1017/S1431927609098973.   

Hao, L., S. Acar, J. Evans, G. Ou, and J. M. Scholey. 2009. “Analysis of Intraflagellar Transport in C. elegans Sensory Cilia.” Methods in Cell Biology 93: 235-266. doi.org/10.1016/S0091-679X(08)93013-2.   

Reed, B. W., M. R. Armstrong, N. D. Browning, G. H. Campbell, J. E. Evans, T. Lagrange, and D. J. Masiel. 2009. “The Evolution of Ultrafast Electron Microscope Instrumentation.” Microscopy and Microanalysis 15 (4): 272-281. doi.org/10.1017/S1431927609090394.   

2008 

Evans, J. E., C. Hetherington, A. Kirkland, L. Y. Chang, H. Stahlberg, and N. Browning. 2008. “Low-Dose Aberration Corrected Cryo-Electron Microscopy of Organic Specimens.” Ultramicroscopy 108 (12): 1636-1644. doi.org/10.1016/j.ultramic.2008.06.004.   

2007  

Chiu, P. L., M. D. Pagel, J. Evans, H. T. Chou, X. Zeng, B. Gipson, H. Stahlberg, and C. M. Nimigean. 2007. “The Structure of the Prokaryotic Cyclic Nucleotide-Modulated Potassium Channel MloK1 at 16 Å Resolution.” Structure 15 (9): 1053-1064. doi.org/10.1016/j.str.2007.06.020.   

Chou, H. T., J. E. Evans, and H. Stahlberg. 2007. “Electron Crystallography of Membrane Proteins.” Methods in Molecular Biology 369: 331-343. doi.org/10.1385/1-59745-294-7:331.   

Runge, K. E., J. E. Evans, Z. Y. He, S. Gupta, K. L. McDonald, H. Stahlberg, P. Primakoff, and D. G. Myles. 2007. “Oocyte Cd9 Is Enriched on the Microvillar Membrane and Required for Normal Microvillar Shape and Distribution.” Developmental Biology 304 (1): 317-325. doi.org/10.1016/j.ydbio.2006.12.041. 

2006  

Evans, J. E., J. J. Snow, A. L. Gunnarson, G. Ou, H. Stahlberg, K. L. McDonald, and J. M. Scholey. 2006. “Erratum: Transition (Journal of Cell Biology (February 27, 2006) 172, 5, (663-669)).” Journal of Cell Biology 175 (5): 837. doi.org/10.1083/jcb.200509115520061120c. 

Evans, J. E., J. J. Snow, A. L. Gunnarson, G. Ou, H. Stahlberg, K. L. McDonald, and J. M. Scholey. 2006. “Functional Modulation of IFT Kinesins Extends the Sensory Repertoire of Ciliated Neurons in Caenorhabditis elegans.” Journal of Cell Biology 172 (5): 663-669. doi.org/10.1083/jcb.200509115.   

Tao, L., A. Mogilner, G. Civelekoglu-Scholey, R. Wollman, J. Evans, H. Stahlberg, and J. M. Scholey. 2006. “A Homotetrameric Kinesin-5, KLP61F, Bundles Microtubules and Antagonizes Ncd in Motility Assays.” Current Biology 16 (23): 2293-2302. doi.org/10.1016/j.cub.2006.09.064.