Kristin E. Burnum-Johnson
Biological Science Area Leader
Kristin Burnum-Johnson is a senior scientist and biological science area leader at the Environmental Molecular Sciences Laboratory. Burnum-Johnson earned her PhD in Biochemistry from Vanderbilt University with Professor Richard M. Caprioli and then completed a postdoctoral fellowship at Pacific Northwest National Laboratory with Richard D. Smith.
Critical challenges in systems biology, ranging from environmental sustainability to human health, may be addressed through the comprehensive and informative view of underlying biological pathways provided by the integration of spatiotemporal multi-omic measurements (i.e., proteomics, metabolomics, and lipidomics). Her research is dedicated to achieving transformative molecular-level insights into environmental and biomedical systems by implementing advanced mass spectrometry (MS) instrumentation. Burnum-Johnson has more than 20 years of experience and more than 80 publications dedicated to the development and evaluation of in situ imaging MS, structural characterization of molecules using ion mobility-MS, and analyses of molecules in complex matrices using high-resolution MS. Her research program is funded by the U.S. Department of Energy (DOE) Biological and Environmental Research (BER) program, the DOE Bioenergy Technologies Office (BETO), and the National Institutes of Health (NIH).
Burnum-Johnson was selected to receive a 2019 Early Career Research Program Award from DOE’s Office of Science. As part of her DOE BER early career research program, she is applying a multi-omics approach to uncover the mechanisms that drive cooperative fungal-bacterial interactions that result in the degradation of lignocellulosic plant material in natural ecosystems. Insights obtained from these studies inform new strategies for producing advanced bioproducts and biofuels.
Research Interests
- MS
- Proteomics
- Metabolomics
- Lipidomics
- Metaproteomics
Education
- PhD in Biochemistry, Vanderbilt University, 2008
- BS in Biochemistry, University of Washington, 2002
Awards and Recognition
Early Career Research Program Award, DOE BER, 2019
Affiliations and Professional Service
- American Society for Mass Spectrometry
- American Chemical Society
Publications
2023
Veličković, M., Wu, R., Gao, Y. et al. Mapping microhabitats of lignocellulose decomposition by a microbial consortium. Nat Chem Biol (2024).
Deng, Shuang, Kim, Joonhoon, et. al. Identification of a specific exporter that enables high production of aconitic acid in Aspergillus pseudoterreus. Metabolic Engineering. 80, 163-172.
Nakayasu, E.S., Gritsenko, M.A., Kim, YM. et al. Elucidating regulatory processes of intense physical activity by multi-omics analysis. Military Med Res 10, 48 (2023).
2022
Pomraning, K. R., Dai, Z., Munoz, N., Kim, Y.-M., Gao, Y., Deng, S., Lemmon, T., Swita, M. S., Zucker, J. D., Kim, J., Mondo, S. J., Panisko, E., Burnet, M. C., Webb-Robertson, B.-J. M., Hofstad, B., Baker, S. E., Burnum-Johnson, K. E., Magnuson, J. K. Itaconic acid production is regulated by LaeA in Aspergillus pseudoterreus. Metabolic Engineering Communications. 15, e00203.
Ling, C., Peabody, G. L., Salvachúa, D., Kim, Y.-M., Kneucker, C. M., Calvey, C. H., Monninger, M. A., Munoz, N. M., Poirier, B. C., Ramirez, K. J., St. John, P. C., Woodworth, S. P., Magnuson, J. K., Burnum-Johnson, K. E., Guss, A. M., Johnson, C. W., Beckham, G. T. Muconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineering. Nature Communications. 13, 4925.
Lee, J.-Y., Mitchell, H. D., Burnet, M. C., Wu, R., Jenson, S. C., Merkley, E. D., Nakayasu, E. S., Nicora, C. D., Jansson, J. K.‡, Burnum-Johnson, K. E. (co-corresponding author)‡, Payne, S. H.‡. Uncovering Hidden Members and Functions of the Soil Microbiome Using De Novo Metaproteomics. Journal of Proteome Research. 21, 2023-35.
Burnum-Johnson, K. E. (co-corresponding author)‡, Conrads, T. P., Drake, R. R., Herr, A. E., Iyengar, R., Kelly, R. T., Lundberg, E., MacCoss, M. J., Naba, A., Nolan, G. P., Pevzner, P. A., Rodland, K. D., Sechi, S., Slavov, N., Spraggins, J. M., Van Eyk, J. E., Vidal, M., Vogel, C., Walt, D. R., Kelleher, N. L.‡. New Views of Old Proteins: Clarifying the Enigmatic Proteome. Molecular & Cellular Proteomics. 21,100254.
2021
Kirby, J., Geiselman, G. M., Yaegashi, J., Kim, J., Zhuang, X., Tran-Gyamfi, M. B., Prahl, J.-P., Sundstrom, E. R., Gao, Y., Munoz, N., Burnum-Johnson, K. E., Benites, V.T., Baidoo, E. E.K. , Fuhrmann, A., Seibel, K., Webb-Robertson, B.-J. M., Zucker, J., Nicora, C. D., Tanjore, D., Magnuson, J. K., Skerker, J. M., Gladden, J. M. Further engineering of R. toruloides for the production of terpenes from lignocellulosic biomass. Biotechnology for Biofuels. 14, 101.
Wu, R., Davison, M. R., Gao, Y., Nicora ,C. D., McDermott, J. E., Burnum-Johnson, K. E., Hofmockel, K. S., Jansson, J. K. Moisture modulates soil reservoirs of active DNA and RNA viruses. Communications Biology. 4, 992.
Sims, A. C., Mitchell, H. D., Gralinski, L. E., Kyle, J. E., Burnum-Johnson, K. E., Lam, M., Fulcher, M.L., West, A., Smith, R. D., Randell, S. H., Metz, T. O., Sheahan, T. P., Waters, K. M., Baric, R. S. Unfolded Protein Response Inhibition Reduces Middle East Respiratory Syndrome Coronavirus-Induced Acute Lung Injury. mBio.12, e01572-21.
Pomraning, K. R., Dai, Z., Munoz, N., Kim, Y.-M., Gao, Y., Deng, S., Kim, J., Hofstad, B. A., Swita, M. S., Lemmon, T., Collett, J. R., Panisko, E. A., Webb-Robertson, B.-J. M., Zucker, J. D., Nicora, C. D., De Paoli, H., Baker, S. E., Burnum-Johnson, K. E., Hillson, N. J., Magnuson, J. K. Integration of Proteomics and Metabolomics Into the Design, Build, Test, Learn Cycle to Improve 3-Hydroxypropionic Acid Production in Aspergillus pseudoterreus. Frontiers in Bioengineering and Biotechnology. 9.
Khadempour, L., Kyle, J. E., Webb-Robertson, B.-J. M., Nicora, C. D., Smith, F. B., Smith, R. D., Lipton, M. S., Currie, C. R.‡, Baker, E. S.‡, Burnum-Johnson, K. E. (co-corresponding author)‡. From Plants to Ants: Fungal Modification of Leaf Lipids for Nutrition and Communication in the Leaf-Cutter Ant Fungal Garden Ecosystem. mSystems. 6, e01307-20.
Tsai, C.-F., Zhang, P., Scholten, D., Martin, K., Wang, Y.-T., Zhao, R., Chrisler, W. B., Patel, D. B., Dou, M., Jia, Y., Reduzzi, C., Liu, X., Moore, R. J., Burnum-Johnson, K. E., Lin, M.-H., Hsu, C.-C., Jacobs, J. M., Kagan, J., Srivastava, S., Rodland, K. D., Wiley, S. H., Qian, W.-J., Smith, R. D., Zhu, Y., Cristofanilli, M., Liu, T., Liu, H., Shi, T. Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics. Communications Biology. 4, 265.
Veličković, D., Chu, R. K., Henkel, C., Nyhuis, A., Tao, N., Kyle, J. E., Adkins, J. N., Anderton, C. R., Paurus, V., Bloodsworth, K., Bramer, L. M., Cornett, D. S., Curtis, W. R., Burnum-Johnson, K. E. (corresponding author). Preserved and variable spatial-chemical changes of lipids across tomato leaves in response to central vein wounding reveals potential origin of linolenic acid in signal transduction cascade. Plant-Environment Interactions. 2, 28-35.
Kim, J., Coradetti, S. T., Kim, Y.-M., Gao, Y., Yaegashi, J., Zucker, J. D., Munoz, N., Zink, E. M., Burnum-Johnson, K. E., Baker, S. E., Simmons, B. A., Skerker, J. M., Gladden, J. M., Magnuson, J. K. Multi-Omics Driven Metabolic Network Reconstruction and Analysis of Lignocellulosic Carbon Utilization in Rhodosporidium toruloides. Frontiers in Bioengineering and Biotechnology. 8.
Odenkirk, M.T., Stratton, K. G., Bramer, L. M., Webb-Robertson, B.-J. M., Bloodsworth, K. J., Monroe, M. E., Burnum-Johnson, K. E., Baker, E. S. From Prevention to Disease Perturbations: A Multi-Omic Assessment of Exercise and Myocardial Infarctions. Biomolecules. 11, 40.
2020
Geiselman G.M., X. Zhuang, J. Kirby, M. Tran-Gyamfi, J. Prahl, E.R. Sundstrom, and Y. Gao, et al. 2020. "Production of ent-kaurene from lignocellulosic hydrolysate in Rhodosporidium toruloides." Microbial Cell Factories 19, no. 1:Article No. 24. PNNL-SA-150034. doi:10.1186/s12934-020-1293-8
Piehowski P.D., Y. Zhu, L.M. Bramer, K.G. Stratton, R. Zhao, D.J. Orton, and R.J. Moore, et al. 2020. "Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-µm spatial resolution." Nature Communications 11, no. 1:Article No. 8. PNNL-SA-138884. doi:10.1038/s41467-019-13858-z
2019
Burnum-Johnson K.E., X. Zheng, J.N. Dodds, J. Ash, D. Fourches, C.D. Nicora, and J.P. Wendler, et al. 2019. "Ion mobility spectrometry and the omics: Distinguishing isomers, molecular classes and contaminant ions in complex samples." Trends in Analytical Chemistry. TrAC 116. PNNL-SA-140985. doi:10.1016/j.trac.2019.04.022
Horta M.A., N. Thieme, Y. Gao, K.E. Burnum-Johnson, C.D. Nicora, M.A. Gritsenko, and M.S. Lipton, et al. 2019. "Broad substrate-specific phosphorylation events are associated with the initial stage of plant cell wall recognition in Neurospora crassa." Frontiers in Microbiology 10. PNNL-SA-143199. doi:10.3389/fmicb.2019.02317
Merkley E.D., K.E. Burnum-Johnson, L.N. Anderson, S.C. Jenson, and K.L. Wahl. 2019. "Uniformly 15N-Labeled Recombinant Ricin A-chain as an Internal Retention Time Standard for Increased Confidence in Forensic Identification of Ricin by Untargeted Nanoflow Liquid Chromatography-Tandem Mass Spectrometry." Analytical Chemistry 91, no. 21:13372-13376. PNNL-SA-145704. doi:10.1021/acs.analchem.9b03389
Singer R.A., L. Arnes, Y. Cui, J. Wang, Y. Gao, M. Guney, and K.E. Burnum-Johnson, et al. 2019. "The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function." Cell Metabolism 30, no. 6:1091-1106.e8. PNNL-SA-146887. doi:10.1016/j.cmet.2019.09.013
Snyder M., S. Lin, A. Posgai, M.A. Atkinson, A. Regev, J. Rood, and O. Rozenblatt-Rosen, et al. 2019. "The human body at cellular resolution: the NIH Human Biomolecular Atlas Program." Nature 574, no. 7777:187-192. PNNL-SA-146510. doi:10.1038/s41586-019-1629-x
Stratton K.G., B.M. Webb-Robertson, L. McCue, B.A. Stanfill, D.M. Claborne, I.G. Godinez, and T. Johansen, et al. 2019. "pmartR: Quality Control and Statistics for Mass Spectrometry-based Biological Data." Journal of Proteome Research 18, no. 3:1418-1425. PNNL-SA-138429. doi:10.1021/acs.jproteome.8b00760
Yin R., K.E. Burnum-Johnson, X. Sun, S.K. Dey, and J. Laskin. 2019. "High Spatial Resolution Imaging of Biological Tissues Using Nanospray Desorption Electrospray Ionization Mass Spectrometry." Nature Protocols 14, no. 12:3445-3470. PNNL-SA-142602. doi:10.1038/s41596-019-0237-4
2018
Duncan K.D., R. Fang, J. Yuan, R.K. Chu, S.K. Dey, K.E. Burnum-Johnson, and I. Lanekoff. 2018. "Quantitative mass spectrometry imaging of prostaglandins as silver ion adducts with nanospray desorption electrospray ionization." Analytical Chemistry 90, no. 12:7246-7252. PNNL-SA-131518. doi:10.1021/acs.analchem.8b00350
Kedia K., J.P. Wendler, E.M. Baker, K.E. Burnum-Johnson, L.G. Jarsberg, K.G. Stratton, and A.T. Wright, et al. 2018. "Application of multiplexed ion mobility spectrometry towards the identification of host protein signatures of treatment effect in pulmonary tuberculosis." Tuberculosis 112. PNNL-SA-137966. doi:10.1016/j.tube.2018.07.005
Kyle J.E., N.A. Aly, X. Zheng, K.E. Burnum-Johnson, R.D. Smith, and E.M. Baker. 2018. "Evaluating lipid mediator structural complexity using ion mobility spectrometry combined with mass spectrometry." Bioanalysis 10, no. 5:279-289. PNNL-SA-130733. doi:10.4155/bio-2017-0245
Menachery V.D., A. Schafer, K.E. Burnum-Johnson, H.D. Mitchell, A.J. Eisfeld-Fenney, K.B. Walters, and C.D. Nicora, et al. 2018. "MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape." Proceedings of the National Academy of Sciences of the United States of America 115, no. 5:E1012-E1021. PNNL-SA-126254. doi:10.1073/pnas.1706928115
Mercer N., T.K. Sigdel, S. Nandoe, C.D. Nicora, K.E. Burnum-Johnson, W. Qian, and M. Sarwal. 2018. "Urinary Virome perturbations in kidney transplantation." Frontiers in Medicine 5. PNNL-SA-130392. doi:10.3389/fmed.2018.00072
Nicora C.D., K.E. Burnum-Johnson, E.S. Nakayasu, C.P. Casey, R.A. White, T. Roy Chowdhury, and J.E. Kyle, et al. 2018. "The MPLEx Protocol for Multi-Omic Analyses of Soil Samples." Journal of Visualized Experiments e57343, no. 135. PNNL-SA-129344. doi:10.3791/57343
2017
Burnum-Johnson K.E., E.M. Baker, and T.O. Metz. 2017. "Characterizing the Lipid and Metabolite Changes Associated with Placental Function and Pregnancy Complications Using Ion Mobility Spectrometry-Mass Spectrometry and Mass Spectrometry Imaging." Placenta 60, no. Supplement 1:S67-S72. PNNL-SA-123563. doi:10.1016/j.placenta.2017.03.016
Burnum-Johnson K.E., J.E. Kyle, A.J. Eisfeld, C.P. Casey, K.G. Stratton, J.F. Gonzalez, and F. Habyarimana, et al. 2017. "MPLEx: A method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling." Analyst 142, no. 3:442-448. PNNL-SA-116063. doi:10.1039/c6an02486f
Eisfeld A.J., P. Halfmann, J.P. Wendler, J.E. Kyle, K.E. Burnum-Johnson, Z. Peralta, and T. Maemura, et al. 2017. "Multi-platform 'Omics Analysis of Human Ebola Virus Disease Pathogenesis." Cell Host & Microbe 22, no. 6:817-829. PNNL-SA-120881. doi:10.1016/j.chom.2017.10.011
Kyle J.E., C.P. Casey, K.G. Stratton, E.M. Zink, Y. Kim, X. Zheng, and M.E. Monroe, et al. 2017. "Comparing Identified and Statistically Significant Lipids and Metabolites in 15-Year Old Serum and Dried Blood Spot Samples for Longitudinal Studies." Rapid Communications in Mass Spectrometry 31, no. 5:447-456. PNNL-SA-121197. doi:10.1002/rcm.7808
Zheng X., R. Wojcik, X. Zhang, Y.M. Ibrahim, K.E. Burnum-Johnson, D.J. Orton, and M.E. Monroe, et al. 2017. "Coupling Front-end Separations, Ion Mobility Spectrometry, and Mass Spectrometry for Enhanced Multidimensional Biological and Environmental Analyses." Annual Review of Analytical Chemistry 10. PNNL-SA-121198. doi:10.1146/annurev-anchem-061516-045212
2016
Burnum-Johnson K.E., S. Nie, C.P. Casey, M.E. Monroe, D.J. Orton, Y.M. Ibrahim, and M.A. Gritsenko, et al. 2016. "Simultaneous Proteomic Discovery and Targeted Monitoring using Liquid Chromatography, Ion Mobility Spectrometry and Mass Spectrometry." Molecular and Cellular Proteomics 15, no. 12:3694-3705. PNNL-SA-118308. doi:10.1074/mcp.M116.061143
Huang E.L., P.D. Piehowski, D.J. Orton, R.J. Moore, W. Qian, C.P. Casey, and X. Sun, et al. 2016. "SNaPP: Simplified Nano-Proteomics Platform for reproducible global proteomic analysis of nanogram protein quantities." Endocrinology 157, no. 3:1307-14. PNNL-SA-111854. doi:10.1210/en.2015-1821
Khadempour L., K.E. Burnum-Johnson, E.S. Baker, C.D. Nicora, B.M. Webb-Robertson, R.A. White, and M.E. Monroe, et al. 2016. "The fungal cultivar of leaf-cutter ants produces specific enzymes in response to different plant substrates." Molecular Ecology 25, no. 22:5795-5805. PNNL-SA-113016. doi:10.1111/mec.13872
Kyle J.E., X. Zhang, K.K. Weitz, M.E. Monroe, Y.M. Ibrahim, R.J. Moore, and J. Cha, et al. 2016. "Uncovering Biologically Significant Lipid Isomers with Liquid Chromatography, Ion Mobility Spectrometry and Mass Spectrometry." Analyst 141, no. 5:1649-1659. PNNL-SA-111991. doi:10.1039/C5AN02062J
Lanekoff I., J. Cha, J.E. Kyle, S.K. Dey, J. Laskin, and K.E. Burnum-Johnson. 2016. "Trp53 deficient mice predisposed to preterm birth display region-specific lipid alterations at the embryo implantation site." Scientific Reports 6. PNNL-SA-116850. doi:10.1038/srep33023
Nakayasu E.S., C.D. Nicora, A.C. Sims, K.E. Burnum-Johnson, Y. Kim, J.E. Kyle, and M.M. Matzke, et al. 2016. "MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses." mSystems 1, no. 3:e00043-16. PNNL-SA-114737. doi:10.1128/mSystems.00043-16
Zhang X., M.V. Romm, X. Zheng, E.M. Zink, Y. Kim, K.E. Burnum-Johnson, and D.J. Orton, et al. 2016. "SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in bio?uids." Clinical Mass Spectrometry 2. PNNL-SA-117436. doi:10.1016/j.clinms.2016.11.002
2015
Aylward F.O., L. Khadempour, D. Tremmel, B.R. McDonald, C.D. Nicora, S. Wu, and R.J. Moore, et al. 2015. "Enrichment and Broad Representation of Plant Biomass-Degrading Enzymes in the Specialized Hyphal Swellings of Leucoagaricus gongylophorus, the Fungal Symbiont of Leaf-Cutter Ants." PLoS One 10, no. 8:e0134752. PNNL-SA-108498. doi:10.1371/journal.pone.0134752
Baker E.S., K.E. Burnum-Johnson, Y.M. Ibrahim, D.J. Orton, M.E. Monroe, R.T. Kelly, and R.J. Moore, et al. 2015. "Enhancing Bottom-up and Top-down Proteomic Measurements with Ion Mobility Separations." Proteomics 15, no. 16:2766-2776. PNNL-SA-107785. doi:10.1002/pmic.201500048
Cha J., K.E. Burnum-Johnson, A. Bartos, Y. Li, E.S. Baker, S.C. Tilton, and B.M. Webb-Robertson, et al. 2015. "Muscle segment homeobox genes direct embryonic diapause by limiting inflammation in the uterus." Journal of Biological Chemistry 290, no. 24:15337-15349. PNNL-SA-107786. doi:10.1074/jbc.M115.655001
Lanekoff I.T., K.E. Burnum-Johnson, M. Thomas, J. Cha, S.K. Dey, P. yang, and M. Prieto, et al. 2015. "Three-Dimensional Imaging of Lipids and Metabolites in Tissues by Nanospray Desorption Electrospray Ionization Mass Spectrometry." Analytical and Bioanalytical Chemistry 407, no. 8:2063-2071. PNNL-SA-100218. doi:10.1007/s00216-014-8174-0
2014
Baker E.S., K.E. Burnum-Johnson, J.M. Jacobs, D.L. Diamond, R.N. Brown, Y.M. Ibrahim, and D.J. Orton, et al. 2014. "Advancing the High Throughput Identification of Liver Fibrosis Protein Signatures Using Multiplexed Ion Mobility Spectrometry." Molecular and Cellular Proteomics 13, no. 4:1119-1127. PNNL-SA-90826. doi:10.1074/mcp.M113.034595
Huang E.L., F.O. Aylward, Y. Kim, B.M. Webb-Robertson, C.D. Nicora, Z. Hu, and T.O. Metz, et al. 2014. "The fungus gardens of leaf-cutter ants undergo a distinct physiological transition during biomass degradation." Environmental Microbiology Reports 6, no. 4:389-95. PNNL-SA-96938. doi:10.1111/1758-2229.12163
Martin J.L., P.A. Yates, R. Soysa, J.F. Alfaro, F. Yang, K.E. Burnum-Johnson, and V.A. Petyuk, et al. 2014. "Metabolic Reprogramming During Purine Stress in the Protozoan Pathogen Leishmania donovani." PLoS Pathogens 10, no. 2:e1003938. PNNL-SA-96975. doi:10.1371/journal.ppat.1003938
2013
Aylward F.O., K.E. Burnum-Johnson, S.G. Tringe, C. Teiling, D. Tremmel, J. Moeller, and J.J. Scott, et al. 2013. "Leucoagaricus gongylophorus Produces Diverse Enzymes for the Degradation of Recalcitrant Plant Polymers in Leaf-Cutter Ant Fungus Gardens." Applied and Environmental Microbiology 79, no. 12:3770-3778. PNNL-SA-92750. doi:10.1128/AEM.03833-12
Duijvesz D., K.E. Burnum-Johnson, M.A. Gritsenko, M. Hoogland, M.S. Vredenbregt-van den Berg, R. Willemsen, and T.n. Luider, et al. 2013. "Proteomic Profiling of Exosomes Leads to the Identification of Novel Biomarkers for Prostate Cancer." PLoS One 8, no. 12:Article No. e82589. PNNL-SA-88219. doi:10.1371/journal.pone.0082589
Isanapong J., S. Hambright, A.G. Willis, A. Boonmee, S.J. Callister, K.E. Burnum-Johnson, and L. Pasa-Tolic, et al. 2013. "Development of an ecophysiological model for Diplosphaera colotermitum TAV2, a termite hindgut Verrucomicrobium." The ISME Journal 7, no. 9:1803-1813. PNNL-SA-98615. doi:10.1038/ismej.2013.74
Lanekoff I.T., K.E. Burnum-Johnson, M. Thomas, J. Short, J.P. Carson, J. Cha, and S.K. Dey, et al. 2013. "High-Speed Tandem Mass Spectrometric in Situ Imaging by Nanospray Desorption Electrospray Ionization Mass Spectrometry." Analytical Chemistry 85, no. 20:9596-9603. PNNL-SA-96267. doi:10.1021/ac401760s
Piehowski P.D., V.A. Petyuk, J.D. Sandoval, K.E. Burnum, G.R. Kiebel, M.E. Monroe, and G.A. Anderson, et al. 2013. "STEPS: A Grid Search Methodology for Optimized Peptide Identification Filtering of MS/MS Database Search Results." Proteomics 13, no. 5:766-770. PNNL-SA-86051. doi:10.1002/pmic.201200096
2012
Aylward F.O., K.E. Burnum, J.J. Scott, G. Suen, S.G. Tringe, S.M. Adams, and K.W. Barry, et al. 2012. "Metagenomic and metaproteomic insights into bacterial communities in leaf-cutter ant fungus gardens." The ISME Journal 6, no. 9:1688-1701. PNNL-SA-82393. doi:10.1038/ismej.2012.10
Baker E.S., T. Liu, V.A. Petyuk, K.E. Burnum-Johnson, Y.M. Ibrahim, G.A. Anderson, and R.D. Smith. 2012. "Mass Spectrometry for Translational Proteomics: Progress and Clinical Implications." Genome Medicine 4. PNNL-SA-86783. doi:10.1186/gm364
Burnum K.E., Y. Hirota, E.S. Baker, M. Yoshie, Y.M. Ibrahim, M.E. Monroe, and G.A. Anderson, et al. 2012. "Uterine deletion of Trp53 compromises antioxidant responses in mouse decidua." Endocrinology 153, no. 9:4568-4579. PNNL-SA-87211. doi:10.1210/en.2012-1335
Diamond D.L., A. Krasnoselski, K.E. Burnum, M.E. Monroe, B.M. Webb-Robertson, J.E. McDermott, and M.M. Yeh, et al. 2012. "Proteome and Computational Analyses Reveal New Insights into the Mechanisms of Hepatitis C Virus Mediated Liver Disease Posttransplantation." Hepatology 56, no. 1:28-38. PNWD-SA-9552. doi:10.1002/hep.25649
Wiedner S.D., K.E. Burnum, L.M. Pederson, L.N. Anderson, S. Fortuin, L.M. Chauvigne-Hines, and A.K. Shukla, et al. 2012. "Multiplexed Activity-based Protein Profiling of the Human Pathogen Aspergillus fumigatus Reveals Large Functional Changes upon Exposure to Human Serum." Journal of Biological Chemistry 287, no. 40:33447-33459. PNNL-SA-87258. doi:10.1074/jbc.M112.394106
2011
Burnum K.E., S.J. Callister, C.D. Nicora, S.O. Purvine, P. Hugenholtz, F. Warnecke, and R.H. Scheffrahn, et al. 2011. "Proteome Insights into the Symbiotic Relationship Between a Captive Colony of Nasutitermes corniger and its Hindgut Microbiome." The ISME Journal 5, no. 1:161-164. PNNL-SA-68831. doi:10.1038/ismej.2010.97
Lennen R.M., M.A. Kruziki, K. Kumar, R.A. Zinkel, K.E. Burnum, M.S. Lipton, and S.W. Hoover, et al. 2011. "Membrane Stresses Induced by Overproduction of Free Fatty Acids in Escherichia coli." Applied and Environmental Microbiology 77, no. 22:8114-8128. PNNL-SA-83349. doi:10.1128/AEM.05421-11
Zhang H., K.E. Burnum, M.L. Luna, B.O. Petritis, J. Kim, W. Qian, and R.J. Moore, et al. 2011. "Quantitative proteomics analysis of adsorbed plasma proteins classifies nanoparticles with different surface properties and size." Proteomics 11, no. 23:4569-4577. PNNL-SA-74159. doi:10.1002/pmic.201100037