William Chrisler

Biomedical Scientist

2024

J. Fu, B. McKinley, B. James, W.B. Chrisler, L.M. Markillie, M.J. Gaffrey, H.D. Mitchell, M. R. Riaz, B. Marcial, G. Orr, K. Swaminathan, and J. Mullet. 2024. “Cell-type-specific transcriptomics uncovers spatial regulatory networks in bioenergy sorghum stems.” Plant Journal 118 (5): 1668 – 1688. https://doi.org/10.1111/tpj.16690

A.W. Sher, J.A. Aufrecht, D. Herrera, A.E. Zimmerman, Y.-M. Kim, N. Munoz, J.B. Trejo, V.L. Paurus, J.B. Cliff, D. Hu, W.B. Chrisler, and R.J. Tournay. 2024. “Dynamic nitrogen fixation in an aerobic endophyte of Populus.” ISME Journal 18 (1): wrad012. https://doi.org/10.1093/ismejo/wrad012

2023

K. Acosta, S. Sorrels, W.B. Chrisler, W. Huang, S. Gilbert, T. Brinkman, T.P. Michael, S.L. Lebeis, and E. Lam. 2023. “Optimization of Molecular Methods for Detecting Duckweed-Associated Bacteria.” Plants 12 (4). https://www.mdpi.com/2223-7747/12/4/872

C.-F. Tsai, Y.-T. Wang, C.-C. Hsu, R.B. Kitata, R.K. Chu, M. Velickovic, R. Zhao, S.M. Williams, W.B. Chrisler, M.L. Jorgensen, R.J. Moore, and Y. Zhu. 2023. “A streamlined tandem tip-based workflow for sensitive nanoscale phosphoproteomics.” Communications Biology 6 (1): 70. https://doi.org/10.1038/s42003-022-04400-x

S.M. Yannarell, E.S. Beaudoin, H.S. Talley, A.A. Schoenborn, G. Orr, C.R. Anderton, W.B. Chrisler, and E.A. Shank. 2023. “Extensive cellular multi-tasking within Bacillus subtilis biofilms.” mSystems 8 (4). https://doi.org/10.1128/msystems.00891-22

O.P. Leiser, D.L. Auberry, E. Bakker, W.B. Chrisler, K. Engbrecht, H. Engelmann, S. Fansler, V. Gerbasi, J. Hansen, C. Hutchinson, J. Hutchison, and M.J. Lancaster. 2023. “Insights from a workplace SARS-CoV-2 specimen collection program, with genomes placed into global sequence phylogeny.” PLoS ONE 18 (4): e0285042. https://doi.org/10.1371/journal.pone.0285042

K. Acosta, S. Sorrels, W.B. Chrisler, W. Huang, S. Gilbert, T. Brinkman, T.P. Michael, S. Lebeis, and E. Lam. 2023. “Optimization of molecular methods for detection and quantification of specific duckweed-bacteria interactions.” bioRxlv. https://doi.org/10.1101/2023.01.04.522651

R.B. Kitata, M. Velickovic, Z. Xu, R. Zhao, D. Scholten, R.K. Chu, D.J. Orton, W.B. Chrisler, J.V. Mathews, P.D. Piehowski, T. Liu, and R.D. Smith. 2023. “Robust collection and processing for label-free single voxel proteomics.” bioRxlv. https://doi.org/10.1101/2023.08.14.553333

B. Leonard, V. Danna, L. Gorham, M. Davison, W.B. Chrisler, D.N. Kim, and V.R. Gerbasi. 2023. “Shaping Nanobodies and Intrabodies against Proteoforms.” Analytical Chemistry 95 (23): 8747 – 8751. https://doi.org/10.1021/acs.analchem.3c00958

P. Xiang, A. Liyu, Y. Kwon, D. Hu, S.M. Williams, D. Velickovic, L.M. Markillie, W.B. Chrisler, L. Pasa-Tolic, and Y. Zhu. 2023. “Spatial Proteomics toward Subcellular Resolution by Coupling Deep Ultraviolet Laser Ablation with Nanodroplet Sample Preparation.” ACS Measurement Science Au 3 (6): 459 – 468. https://doi.org/10.1021/acsmeasuresciau.3c00033

J. Fu, B. McKinley, B. James, W.B. Chrisler, L.M. Markillie, M.J. Gaffrey, H.D. Mitchell, G. Orr, K. Swaminathan, J. Mullet, and A. Marshall-Colon. 2023. “The stem cell-type transcriptome of bioenergy sorghum reveals the spatial regulation of secondary cell wall networks.” bioRxlv. https://doi.org/10.1101/2023.04.22.537921

2022

C.-F. Tsai, Y.-T. Wang, C.-C. Hsu, R.B. Kitata, R.K. Chu, M. Velickovic, R. Zhao, S.M. Williams, W.B. Chrisler, M.L. Jorgensen, R.J. Moore, and Y. Zhu. 2022. “A streamlined tandem tip-based workflow for sensitive nanoscale phosphoproteomics.” bioRxlv. https://doi.org/10.1101/2022.04.12.488038

S. Gilbert, A. Poulev, W.B. Chrisler, K. Acosta, G. Orr, S. Lebeis, and E. Lam. 2022. “Auxin-Producing Bacteria from Duckweeds Have Different Colonization Patterns and Effects on Plant Morphology.” Plants 11 (6): 721. https://doi.org/10.3390/plants11060721

C.E. Anderson, J. Zhang, L.M. Markillie, H.D. Mitchell, W.B. Chrisler, M.J. Gaffrey, G. Orr, and J.S. Schilling. 2022. “Capturing an Early Gene Induction Event during Wood Decay by the Brown Rot Fungus Rhodonia placenta.” Applied and Environmental Microbiology 88 (8). https://doi.org/10.1128/aem.00188-22

S.M. Yannarell, E.S. Beaudoin, H.S. Talley, A.A. Schoenborn, G. Orr, C.R. Anderton, W.B. Chrisler, and E.A. Shank. 2022. bioRxlv. https://doi.org/10.1101/2022.09.02.506450

J. Woo, G.C. Clair, S.M. Williams, S. Feng, C.-F. Tsai, R.J. Moore, W.B. Chrisler, R.D. Smith, R.T. Kelly, L. Pasa-Tolic, C. Ansong, and Y. Zhu. 2022. “Three-dimensional feature matching improves coverage for single-cell proteomics based on ion mobility filtering.” Cell Systems 13 (5): 426 – 434.e4. https://doi.org/10.1016/j.cels.2022.02.003

2021

A.D. McNaughton, E.L. Bredeweg, J. Manzer, J. Zucker, N. Munoz Munoz, M.C. Burnet, E.S. Nakayasu, K.R. Ponraning, E.D. Merkley, Z. Dai, W.B. Chrisler, and S.E. Baker. 2021. “Bayesian Inference for IntegratingYarrowia lipolyticaMultiomics Datasets with Metabolic Modeling.” ACS Synthetic Biology 10 (11): 2968 – 2981. https://doi.org/10.1021/acssynbio.1c00267

V.K. Balasubramanian, S.O. Purvine, Y. Liang, R.T. Kelly, L. Pasa-Tolic, W.B. Chrisler, E. Blumwald, C.N. Stewart, Y. Zhu, and A.H. Ahkami. 2021. “Cell-Type-Specific Proteomics Analysis of a Small Number of Plant Cells by Integrating Laser Capture Microdissection with a Nanodroplet Sample Processing Platform.” Current Protocols 1 (5): e153. https://doi.org/10.1002/cpz1.153

S.P. Lillington, W.B. Chrisler, C.H. Haitjema, S.P. Gilmore, C.R. Smallwood, V. Shutthanandan, J.E. Evans, and M.A. O’malley. 2021. “Cellulosome localization patterns vary across life stages of anaerobic fungi.” mBio 12 (3): e00832-21. https://doi.org/10.1128/mBio.00832-21

D. Hu, Y. Cui, L.M. Markillie, W.B. Chrisler, Q. Wang, R. Hatzenpichler, and G. Orr. 2021. “Counting mRNA Copies in Intact Bacterial Cells by Fluctuation Localization Imaging-Based Fluorescence In Situ Hybridization (fliFISH).” Methods in Molecular Biology 2246: 237 – 247. https://doi.org/10.1007/978-1-0716-1115-9_15

K. Martin, T. Zhang, T.-T. Lin, A.N. Habowski, R. Zhao, C.-F. Tsai, W.B. Chrisler, R.L. Sontag, D.J. Orton, Y.-J. Lu, K.D. Roland, and B. Yang. 2021. “Facile One-Pot Nanoproteomics for Label-Free Proteome Profiling of 50-1000 Mammalian Cells.” Journal of Proteome Research 20 (9): 4452 – 4461. https://doi.org/10.1021/acs.jproteome.1c00403

J. Woo, G.C. Clair, S.M. Williams, S. Feng, C.-F. Tsai, R.J. Moore, W.B. Chrisler, R.D. Smith, R.T. Kelly, L. Pasa-Tolic, C. Ansong, and Y. Zhu. 2021. “Robust, sensitive, and quantitative single-cell proteomics based on ion mobility filtering.” bioRxlv. https://doi.org/10.1101/2021.01.30.428333

C.-F. Tsai, P. Zhang, D. Scholten, K. Martin, Y.-T. Wang, R. Zhao, W.B. Chrisler, D.B. Patel, M. Dou, Y. Jia, C. Reduzzi, and X. Liu. 2021. Communications Biology 4 (1): 265. https://doi.org/10.1038/s42003-021-01797-9

2020

C.-F. Tsai, R. Zhao, S.M. Williams, R.J. Moore, K. Schultz, W.B. Chrisler, L. Pasa-Tolic, K.D. Roland, R.D. Smith, T. Shi, Y. Zhu, and T. Liu. 2020. “An Improved Boosting to Amplify Signal with Isobaric Labeling (iBASIL) Strategy for Precise Quantitative Single-cell Proteomics.” Molecular and Cellular Broteomics 19 (5): 828 – 838. https://doi.org/10.1074/mcp.RA119.001857

S.M Williams,  A.V. Liyu, C.-F. Tsai, R.J. Moore, D.J. Orton, W.B. Chrisler, M.J. Gaffrey, T. Liu, R.D. Smith, R.T. Kelly, L. Pasa-Tolic, and Y. Zhu. 2020. “Automated Coupling of Nanodroplet Sample Preparation with Liquid Chromatography-Mass Spectrometry for High-Throughput Single-Cell Proteomics.” Analytical Chemistry 92 (15): 10588 – 10596. https://doi.org/10.1021/acs.analchem.0c01551

K. Martin, T. Zhang, P. Zhang, W.B. Chrisler, F.L. Thomas, F. Liu, T. Liu, W.-J. Qian, R.D. Smith, and T. Shi. 2020. “Carrier-assisted one-pot sample preparation for targeted proteomics analysis of small numbers of human cells.” Journal of Visualized Experiments 2020 (165): 1 – 15. https://doi.org/10.3791/61797

S.E. Taylor, C.I Pearce, K.A. Sanguinet, D. Hu, W.B. Chrisler, Y.-M. Kim, Z. Wang, and M. Flury. 2020. “Polystyrene nano- and microplastic accumulation at Arabidopsis and wheat root cap cells, but no evidence for uptake into roots.” Environmental Science: Nano 2020 (7): 1942 – 1953. https://doi.org/10.1039/d0en00309c

2019

P. Zhang, M.J. Gaffrey, Y. Zhu, W.B. Chrisler, T.J. Fillmore, L. Yi, C.D. Nicora, T. Zhang, H. Wu, J. Jacobs, K. Tang, and J. Kagan. 2019. “Carrier-Assisted Single-Tube Processing Approach for Targeted Proteomics Analysis of Low Numbers of Mammalian Cells.” Analytical Chemistry 91 (2): 1441 – 1451. https://doi.org/10.1021/acs.analchem.8b04258

C.J. Brislawn, E.B. Graham, K. Dana, P. Ihardt, S.J. Fansler, W.B. Chrisler, J..B. Cliff, J.C. Stegen, J.J. Moran, and H.C. Bernstein. 2019. “Forfeiting the priority effect: turnover defines biofilm community succession.” ISME Journal 13 (7): 1865 – 1877. https://doi.org/10.1038/s41396-019-0396-x

M Dou, G. Clair, C.-F. Tsai, K. Zu, W.B. Chrisler, R.L. Sontag, R. Zhao, R.J. Moore, T. Liu, L. Pasa-Tolic, R.D. Smith, and T. Shi. 2019. “High-Throughput Single Cell Proteomics Enabled by Multiplex Isobaric Labeling in a Nanodroplet Sample Preparation Platform.” Analytical Chemistry 91 (20): 13119 – 13127. https://doi.org/10.1021/acs.analchem.9b03349

P. Bohutskyi, R.S. McClure, E.A. Hill, W.C. Nelson, W.B. Chrisler, J.R. Nunez, R.S. Renslow, M.A. Charania, S.R. Lindermann, and A.S. Beliaev. 2019. “Metabolic effects of vitamin B₁₂ on physiology, stress resistance, growth rate and biomass productivity of Cyanobacterium stanieri planktonic and biofilm cultures.” Algal Research 42: 101580. https://doi.org/10.1016/j.algal.2019.101580

A.A. Han, C. Timchalk, Z.A. Carver, T.J. Weber, K.J. Tyrrell, R.L. Sontag, T. Gibbins, W.B. Chrisler, K.K. Weitz, D. Du, Y. Lin, and J.N. Smith. 2019. “Physiologically Based Pharmacokinetic Modeling of Salivary Concentrations for Noninvasive Biomonitoring of 2,4-Dichlorophenoxyacetic Acid (2,4-D).” Toxicological Sciences 172 (2): 330 – 343. https://doi.org/10.1093/toxsci/kfz206

T.J. Weber, W.-J. Qian, J.N. Smith, M.A. Gritsenko, D. Hu, W.B. Chrisler, and C. Timchalk. 2019. “Stable Acinar Progenitor Cell Model Identifies Treacle-Dependent Radioresistance.” Radiation Research 192 (2): 135 – 144. https://doi.org/10.1667/RR15342.1

2018

Z.A. Carver, A.A. Han, C. Timchalk, T.J. Weber, K.J. Tyrrell, R.L. Sontag, T. Luders, W.B. Chrisler, K.K. Weitz, and J.N. Smith. 2018. “Evaluation of non-invasive biomonitoring of 2,4-Dichlorophenoxyacetic acid (2,4-D) in saliva.” Toxicology 410: 171 -181. https://doi.org/10.1016/j.tox.2018.08.003

Y. Cui, D. Hu, L.M. Markillie, W.B. Chrisler, M.J. Gaffrey, C. Ansong, L. Sussel, and G. Orr. 2018. “Fluctuation localization imaging-based fluorescence in situ hybridization (fliFISH) for accurate detection and counting of RNA copies in single cells.” Nucleic Acids Research 46 (2): e7. https://doi.org/10.1093/nar/gkx874

C.J. Brislawn, E.B. Graham, K. Dana, P. Ihardt, S.J. Fansler, W.B. Chrisler, J.B. Cliff, J.C. Stegen, J.J. Moran, and H.C. Bernstein. 2018. “Forfeiting the founder effect: Turnover defines biofilm community succession.” bioRxlv. https://doi.org/10.1101/282574

E.S. Melby, Y. Cui, J. Borgatta, A.C. Mensch, M.N. Hang, W.B. Chrisler, A. Dohnalkova, J.M. Van Gilder, C.M. Alvarez, J.N. Smith, R.J. Hamers, and G. Orr. 2018. “Impact of lithiated cobalt oxide and phosphate nanoparticles on rainbow trout gill epithelial cells.” Nanotoxicology 12 (10): 1166 – 1181. https://doi.org/10.1080/17435390.2018.1508785

J.C. Stegen, T. Johnson, J.K. Fredrickson, M.J. Wilkins, A.E. Konopka, W.C. Nelson, E.V. Arntzen, W.B. Chrisler, R.K. Chu, S.J. Fansler, E.B. Graham. and D.W. Kennedy. 2018. “Influences of organic carbon speciation on hyporheic corridor biogeochemistry and microbial ecology.” Nature Communications 9 (1): 585. https://doi.org/10.1038/s41467-018-02922-9

C.R. Smallwood, J.-H. Chen, N. Kumar, W.B. Chrisler, S.O. Purvine, J.E. Kyle, C.D. Nicora, R. Boudreau, A. Ekman, K.K. Hixon, R.J. Moore, and G. McDermott. 2018. “Integrated systems biology and imaging of the smallest free-living eukaryote Ostreococcus tauri.” bioRxlv. https://doi.org/10.1101/293704

C.R. Smallwood, E.A. Hill, W.B. Chrisler, J. Brookreson, and J.E. Evans. 2018. “Optimizing bioreactor growth of the smallest eukaryote.” bioRxlv. https://doi.org/10.1101/291211

C.R. Smallwood, W.B. Chrisler, J.-H. Chen, E. Patello, M. Thomas, R. Boudreau, A. Ekman, H. Wang, G. McDermott, and J.E. Evans. 2018. “Ostreococcus tauri is a high-lipid content green algae that extrudes clustered lipid droplets.” bioRxlv. https://doi.org/10.1101/249052

N.Kahn, Y. Maezato, R.S. McClure, C.J. Brislawn, J.M. Mobberley, N. Isern, W.B. Chrisler, L.M. Markillie, B.M. Barney, H.-S. Song, W.C. Nelson, and H.C. Bernstein. 2018. “Phenotypic responses to interspecies competition and commensalism in a naturally-derived microbial co-culture.” Scientific Reports 8 (1): 297. https://doi.org/10.1038/s41598-017-18630-1

Y. Zhu, G. Clair, W.B. Chrisler, Y. Shen, R. Zhao, A.K. Shukla, R.J. Moore, R.S. Misra, G.S. Pryhuber, R.D. Smith, C. Ansong, and R.T. Kelly. 2018. “Proteomic Analysis of Single Mammalian Cells Enabled by Microfluidic Nanodroplet Sample Preparation and Ultrasensitive NanoLC-MS.” Agewandte Chemie – International Edition 57 (38): 12370 – 12374. https://doi.org/10.1002/anie.201802843

J.C. Stegen, T. Johnson, J.K. Fredrickson, M.J. Wilkins, A.E. Konopka, W.C. Nelson, E.V. Arntzen, W.B. Chrisler, R.K. Chu, S.J. Fansler, E.B. Graham, and D.W. Kennedy. 2018. “Publisher Correction: Influences of organic carbon speciation on hyporheic corridor biogeochemistry and microbial ecology (Nature Communications (2018) DOI: 10.1038/s41467-018-02922-9).” Nature Communications 9 (1): 1034. https://doi.org/10.1038/s41467-018-03572-7.

Y. Liang, Y. Zhu, M. Dou, K. Xu, R.K. Chu, W.B. Chrisler, R. Zhao, K.K. Hixon, and R.T. Kelly. 2018. “Spatially Resolved Proteome Profiling of <200 Cells from Tomato Fruit Pericarp by Integrating Laser-Capture Microdissection with Nanodroplet Sample Preparation.” Analytical Chemistry 90 (18): 11106 – 11114. https://doi.org/10.1021/acs.analchem.8b0300

Y. Zhu, M. Dou, P.D. Piehowski, Y. Liang, F. Wang, R.K. Chu, W.B. Chrisler, J.N. Smith, K.C. Schwarz, Y. Shen, A.K. Shukla, and R.J. Moore. 2018. “Spatially resolved proteome mapping of laser capture microdissected tissue with automated sample transfer to nanodroplets.” Molecular and Cellular Proteomics 17 (9): 1864 – 1874. https://doi.org/10.1074/mcp.TIR118.000686

2017

E.A. Hill, W.B. Chrisler, A.S. Beliaev, and H.C. Bernstein. 2017. “A flexible microbial co-culture platform for simultaneous utilization of methane and carbon dioxide from gas feedstocks.” Bioresource Technology 228: 250 – 256. https://doi.org/10.1016/j.biortech.2016.12.111

J.E. Kowalczyk, C. Khosravi, S. Purvine, A. Dohnalkova, W.B. Chrisler, G. Orr, E. Robinson, E. Zink, A. Wiebenga, M. Peng, E. Battaglia, and S. Baker. 2017. “High resolution visualization and exo-proteomics reveal the physiological role of XlnR and AraR in plant biomass colonization and degradation by Aspergillus niger.” Environmental Microbiology 19 (11): 4587 – 4598. https://doi.org/10.1111/1462-2920.13923

R.S. Renslow, M.J. Marshall, A.E. Tucker, W.B. Chrisler, and X.-Y. Yu. 2017. “In situ nuclear magnetic resonance microimaging of live biofilms in a microchannel.” Analyst 142 (13): 2363 – 2371. https://doi.org/10.1039/c7an00078b

H.C. Bernstein, R.S. McClure, V. Thiel, N.C. Sadler, Y.-M. Kim, W.B. Chrisler, E.A. Hill, D.A. Bryant, M.F. Romine, J.K. Jansson, J.K. Fredrickson, and A.S. Beliaev. 2017. “Indirect interspecies regulation: Transcriptional and physiological responses of a cyanobacterium to heterotrophic partnership.” mSystems 2(2): e00181. https://doi.org/10.1128/mSystems.00181-16

M. Liberton, W.B. Chrisler, C.D. Nicora, R.J. Moore, R.D. Smith, D.W. Koppenaal, H.B. Pakrasi, and J.M. Jacobs. 2017. “Phycobilisome truncation causes widespread proteome changes in Synechocystis sp. PCC 6803.” PLoS ONE 12 (3): e0173251. https://doi.org/10.1371/journal.pone.0173251

S.R. Lindermann, J.M. Mobberley, J.K. Cole, L.M. Markille, R.C. Taylor, E. Huang, W.B. Chrisler, H.S. Wiley, M.S. Lipton, W.C. Nelson, J.K. Fredrickson, and M.F. Romine. 2017. “Predicting species-resolved macronutrient acquisition during succession in a model phototrophic biofilm using an integrated 'omics approach.” Frontiers in Microbiology 8 (JUN): 1020. https://doi.org/10.3389/fmicb.2017.01020

M.J. Boenisch, K.L. Broz, S.O. Purvine, W.B. Chrisler, C.D. Nicora, L.R. Connolly, M. Freitag, S.E. Baker, and H.C. Kristler. 2017. “Structural reorganization of the fungal endoplasmic reticulum upon induction of mycotoxin biosynthesis.” Scientific Reports 7: 44296. https://doi.org/10.1038/srep44296

2016

H.D. Mitchell, L.M. Markillie, W.B. Chrisler, M.J. Gaffrey, D. Hu, C.J. Szymanski, Y. Xie, E.S. Melby, A. Dohnalkova, R.C. Taylor, E.K. Grate, and S.K. Cooley. 2016. “Cells Respond to Distinct Nanoparticle Properties with Multiple Strategies As Revealed by Single-Cell RNA-Seq.” ACS Nano 10 (11): 10173 – 10185. https://doi.org/10.1021/acsnano.6b05452

T. Shi, M. Niepel, J.E. McDermott, Y. Gao, C.D. Nicora, W.B. Chrisler, L.M. Markillie, V.A. Petyuk, R.D. Smith, K.D. Rodland, P.K. Sorger, and W.J. Qian. 2016. “Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway.” Science Signaling 9 (436). https://doi.org/10.1126/scisignal.aaf0891

J.C. Stegen, J.K. Fredrickson, M.J. Wilkins, A.E. Konopka, W.C. Nelson, E.V. Arntzen, W.B. Chrisler, R.K. Chu, R.E. Danczak, S.J. Fansler, D.W. Kennedy, and C.T. Resch. 2016. “Groundwater-surface water mixing shifts ecological assembly processes and stimulates organic carbon turnover.” Nature Communications 7 (11237). https://doi.org/10.1038/ncomms11237

H.C. Bernstein, R.S. McClure, E.A. Hill, L.M. Markillie, W.B. Chrisler, M.F. Romine, J.E. McDermott, M.C. Posewitz, D.A. Bryant, A.E. Konopka, J.K. Fredrickson, and A.S. Beliaev. 2016. “Unlocking the constraints of cyanobacterial productivity: Acclimations enabling ultrafast growth.” MBio 7 (4): e00949-16. https://doi.org/10.1128/mBio.00949-16

2015

C. Mihai, W.B. Chrisler, Y. Xie, D. Hu, C.J. Szymanski, A. Tolic, J.A. Klein, J.N. Smith, B.J. Tarasevich, and G. Orr. 2015. “Intracellular accumulation dynamics and fate of zinc ions in alveolar epithelial cells exposed to airborne ZnO nanoparticles at the air-liquid interface.” Nanotoxicology 9 (1): 9 – 22. https://doi.org/10.3109/17435390.2013.859319

K.H. Jacobson, I.L. Gunsolus, T.R. Kuech, J.M. Troiano, E.S. Melby, S.E. Lohse, D. Hu, W.B. Chrisler, C.J. Murphy, G. Orr, F.M Geiger, and C.L. Haynes. 2015. “Lipopolysaccharide Density and Structure Govern the Extent and Distance of Nanoparticle Interaction with Actual and Model Bacterial Outer Membranes.” Environmental Science and Technology 49 (17): 10642 – 10650. https://doi.org/10.1021/acs.est.5b01841

T. Shi, Y. Gao, M.J. Gaffrey, C.D. Nicora, T.L. Fillmore, W.B. Chrisler, M.A. Gritsenko, C. Wu, J. He, K.J. Bloodsworth, R. Zhao, and D.G. Camp. 2015. “Sensitive targeted quantification of ERK phosphorylation dynamics and stoichiometry in human cells without affinity enrichment.” Analytical Chemistry 87 (2): 1103 – 1110. https://doi.org/10.1021/ac503797x

C. Von Neubeck, M.J. Geniza, P.M. Kauer, R.J. Robinson, W.B. Chrisler, and M.B. Sowa. 2015. “The effect of low dose ionizing radiation on homeostasis and functional integrity in an organotypic human skin model.” Mutation Research – Fundamental and Molecular Mechanisms of Mutagenesis 775: 10 – 18. https://doi.org/10.1016/j.mrfmmm.2015.03.003

2014

M.J. Marshall, S.M. Belchik, A.E. Tucker, W.B. Chrisler, M. Thomas, R.S. Renslow, A.P. Kuprat, A.C. Dohnalkova, and C.J. Hirschmugl. 2014. “Chemical imaging of biofilms: The integration of synchrotron imaging, electron microscopy and nuclear magnetic resonance (NMR) technologies.” Microscopy and Microanalysis 20 (3): 1178 – 1179. https://doi.org/10.1017/S1431927614007624

X. Hua, X. Yu, Z. Wang, L. Yang, B. Liu, Z. Zhu, A.E. Tucker, W.B. Chrisler, E.A. Hill, T. Thevuthasan, Y. Lin, and S. Liu. 2014. “In situ molecular imaging of a hydrated biofilm in a microfluidic reactor by ToF-SIMS.” Analyst 139 (7): 1609 – 1613. https://doi.org/10.1039/c3an02262e

A.S. Beliaev, M.F. Romine, M. Serres, H.C. Bernstein, B.E. Linggi, L.M. Markillie, N.G. Isern, W.B. Chrisler, L.A. Kucek, E.A. Hill, G.E. Pinchuk, and D.A. Bryant. 2014. “Inference of interactions in cyanobacterial-heterotrophic co-cultures via transcriptome sequencing.” ISME Journal 8 (11): 2243 – 2255. https://doi.org/10.1038/ismej.2014.69

N.C. Sadler, M.R. Melnicki, M.H. Serres, E.D. Merkley, W.B. Chrisler, E.A. Hill, M.F. Romine, S. Kim, E.M. Zink, S. Datta, R.D. Smith, and A.S. Beliaev. 2014. “Live cell chemical profiling of temporal redox dynamics in a photoautotrophic cyanobacterium.”  ACS Chemical Biology 9 (1): 291 – 300. https://doi.org/10.1021/cb400769

2013

D.G. Welkie, D.M. Sherman, W.B. Chrisler, G. Orr, and L.A. Sherman. 2013. “Analysis of carbohydrate storage granules in the diazotrophic cyanobacterium Cyanothece sp. PCC 7822.” Photosynthesis Research 118 (1-2): 25 – 36. https://doi.org/10.1007/s11120-013-9941-z

K.M. Waters, D.L. Stenoien, M.B. Sowa, C. Von Neubeck, W.B. Chrisler, R. Tan, R.L. Sontag, and T.J. Weber. 2013. “ Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.” Radiation Research 179 (1): 53 – 61. https://doi.org/10.1667/RR3056.1

C. Von Neubeck, H. Shankaran, M.J. Geniza, P.M. Kauer, R.J. Robinson, W.B. Chrisler, and W.B. Sowa. 2013. “Integrated experimental and computational approach to understand the effects of heavy ion radiation on skin homeostasis.” Integrative Biology (United Kingdom) 5 (10): 1229 – 1243. https://doi.org/10.1039/c2mb25190f

2012

Y. Xie, N.G. Williams, A. Tolic, W.B. Chrisler, J.G. Teeguarden, B.L.S. Maddux, J.G. Pounds, and A. Laskin. 2012. “ Aerosolized ZnO nanoparticles induce toxicity in alveolar type II epithelial cells at the air-liquid interface.” Toxicological Sciences 125 (2): 450 – 461. https://doi.org/10.1093/toxsci/kfr251

C. Von Neubeck, H. Shankaran, N.J. Karin, P.M. Kauer, W.B. Chrisler, X. Wang, R.J. Robinson, K.M. Waters, S.C. Tilton, and M.B. Sowa. 2012. “Cell type-dependent gene transcription profile in a three-dimensional human skin tissue model exposed to low doses of ionizing radiation: Implications for medical exposures.” Environmental and Molecular Mutagenesis 53 (4): 247 – 259. https://doi.org/10.1002/em.21682

H. Shankaran, Y. Zhang, W.B. Chrisler, J.A. Ewald, H.S. Wiley, and H. Resat. 2012. “Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics.” Molecular BioSystems 8 (11): 2868 – 2882. https://doi.org/10.1039/c2mb25190f

2011

G.A. Orr, W.B. Chrisler, K.J Cassens, R. Tan, B.J. Tarasevich, and L.M Markillie. 2011. “Cellular recognition and trafficking of amorphous silica nanoparticles by macrophage scavenger receptor a.” Nanotoxicology 5 (3): 296 – 311. https://doi.org/10.3109/17435390.2010.513836

J.H. Miller, W.B. Chrisler, X. Wang, and M.B. Sowa. 2011. “Confocal microscopy for modeling electron microbeam irradiation of skin.” Radiation and Environmental Biophysics 50 (3): 365 – 369. https://doi.org/10.1007/s00411-011-0371-z

H. Jin, Y. Yu, W.B. Chrisler, Y. Xiong, D. Hu, and C. Lei. 2011. “Delivery of microRNA-10b with polylysine nanoparticles for inhibition of breast cancer cell wound healing.” Breast Cancer: Basic and Clinical Research 5 (1). https://doi.org/10.4137/BCBCR.S8513

H. Shankaran, W.B. Chrisler, R.L. Sontag, and T.J. Weber. 2011. “ Inhibition of ERK oscillations by ionizing radiation and reactive oxygen species.” Molecular Carcinogenesis 50 (6): 424 – 432. https://doi.org/10.1002/mc.20724

J.H. Miller, A. Suleiman, W.B. Chrisler, and M.B. Sowa. 2011. “Simulation of electron-beam irradiation of skin tissue model.” Radiation Research 175 (1): 113 – 118. https://doi.org/10.1667/RR2339.1

2010

T.J. Weber, H. Shankaran, H.S. Wiley, L.K. Opresko, W.B. Chrisler, and R.D. Quesenberry. 2010. “Basic fibroblast growth factor regulates persistent ERK oscillations in premalignant but not malignant JB6 cells.” Journal of Investigative Dermatology 130 (5): 1444 – 1456. https://doi.org/10.1038/jid.2009.383

P.M. Hinderliter, K.R. Minard, G. Orr, W.B. Chrisler, B.D. Thrall, J.G. Pounds, and J.G. Teeguarden. 2010. “ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies.” Particle and Fibre Toxicology 7 (36). https://doi.org/10.1186/1743-8977-7-36

M.B. Sowa, W.B. Chrisler, K.D. Zens, E.J. Ashjian, and L.K. Opresko. 2010. “Three-dimensional culture conditions lead to decreased radiation induced cytotoxicity in human mammary epithelial cells.” Assay and Drug Development Technologies 8 (4): 409 – 410. https://doi.org/10.1089/adt.2010.0804.lr

M.B. Sowa, W.B. Chrisler, K.D. Zens, E.J. Ashjian, and L.K. Opresko. 2010. “Three-dimensional culture conditions lead to decreased radiation induced cytotoxicity in human mammary epithelial cells.” Mutation Research – Fundamental and Molecular Mechanisms of Mutagenesis 687 (1-2): 78 – 83. https://doi.org/10.1016/j.mrfmmm.2010.03.004

2009

K.M. Waters, T. Ruimin, L.K. Opresko, R.D. Quesenberry, S. Bandyopadhyay, W.B. Chrisler, and T.J. Weber. 2009. “Cellular dichotomy between anchorage-independent growth responses to bFGF and TPA reflects molecular switch in commitment to carcinogenesis.” Molecular Carcinogenesis 48 (11): 1059 – 1069. https://doi.org/10.1002/mc.20558

Y. Zhang, L. Opresko, H. Shankaran, W.B. Chrisler, H.S. Wiley, and H. Resat. 2009. “HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells.” BMC Cell Biology 10: 78. https://doi.org/10.1186/1471-2121-10-78

S.A. Karagiosis, W.B. Chrisler, N. Bollinger, and N.J. Karin. 2009. “Lysophosphatidic acid-induced ERK activation and chemotaxis in MC3T3-E1 preosteoblasts are independent of EGF receptor transactivation.” Journal of Cellular Physiology 219 (3): 716 – 723. https://doi.org/10.1002/jcp.21720

H. Shankaran, D.L. Ippolito, W.B. Chrisler, H. Resat, N. Bollinger, L.K. Opresko, and H.S. Wiley. 2009. “ Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor.” Molecular Systems Biology 5 (332). https://doi.org/10.1038/msb.2009.90

2007

J.R. Coleman, D.E. Culley, W.B. Vhrisler, and F.J. Brockman. 2007. “mRNA-targeted fluorescent in situ hybridization (FISH) of Gram-negative bacteria without template amplification or tyramide signal amplification.” Journal of Microbiological Methods 71 (3): 246 – 255. https://doi.org/10.1016/j.mimet.2007.09.011

2005

T.J. Weber, R.W. Siegel, L.M. Markillie, W.B. Chrisler, X.C. Lei, and N.H. Colburn. 2005. “A paracrine signal mediates the cell transformation response to low dose gamma radiation in JB6 cells.” Molecular Carcinogenesis 43 (1): 31 – 37. https://doi.org/10.1002/mc.20092

J. Dong, L.K. Opresko, W.B. Chrisler, G. Orr, R.D. Quesenberry, D.A. Lauffenburger, and H.S. Wiley. 2005 “The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode.” Molecular Biology of the Cell 16 (6): 2984 – 2998. https://doi.org/10.1091/mbc.E04-11-0994

2004

M. Jasionowski, K. Krzyminski, W.B. Chrisler, L.M. Markille, J. Morris, and A. Gutowska. 2004. “Thermally-reversible gel for 3-D cell culture of chondrocytes.” Journal of Materials Science: Materials in Medicine 15 (5): 575 – 582. https://doi.org/10.1023/B:JMSM.0000026379.24560.a2

2002

T.J. Weber, L.M. Markillie, W.B. Chrisler, G.A. Vielhauer, and J.W. Regan. 2002. “Modulation of JB6 mouse epidermal cell transformation response by the prostaglandin F_2α receptor.” Molecular Carcinogenesis 35 (4): 163 – 172. https://doi.org/10.1002/mc.10079

2001

A.L. Brooks, S. Bao, K. Rithidech, W.B. Chrisler, L.A. Couch, and L.A. Braby. 2001. “Induction and repair of HZE induced cytogenetic damage.” Physica Medica 17 (1): 183 – 184. https://www.scopus.com/record/display.uri?eid=2-s2.0-0034845886&origin=inward&txGid=a0dca59ffb9bb21537e066e59b6ff3dd

T.P. Conrads, K. Alving, T.D. Veenstra, M.E. Belov, G.A. Anderson, D.J. Anderson, M.S. Lipton, L. Pasa-Tolic, H.R. Udseth, W.B. Chrisler, B.D. Thrall, and R.D. Smith. 2001. “Quantitative analysis of bacterial and mammalian proteomes using a combination of cysteine affinity tags and ¹⁵N-metabolic labeling.” Analytical Chemistry 73 (9): 2132 – 2139. https://doi.org/10.1021/ac001487x

1998

D.L. Miller, A.R. Williams, J.E. Morris, and W.B. Chrisler. 1998. “Sonoporation of erythrocytes by lithotripter shockwaves in vitro.” Ultrasonics 36 (9): 947 – 952. https://doi.org/10.1016/S0041-624X(98)00017-1

1997

A.L. Brooks, S. Bao, P.W. Harwood, B.H. Wood, W.B. Chrisler, and K.M. Groch. 1997. “Comparative Clastogenic Sensitivity of Respiratory Tract Cells to Gamma Rays.” Radiation Research Society 148 (1): 90-097. https://doi.org/10.2307/3579542

A.L. Brooks, S. Bao, P.W. Harwood, B.H. Wood, M.A. Kahn, F.T. Cross, R.A. Gies, and W.B. Chrisler. 1997. “Induction of micronuclei in respiratory tract following radon inhalation.” International Journal of Radiation Biology 72 (5): 485 - 495. https://doi.org/10.1080/095530097142988

D.L. Miller, R. A. Gies, and W. B. Chrisler. 1997. “Ultrasonically induced hemolysis at high cell and gas body concentrations in a thin-disc exposer chamber.” Ultrasound in Medicine and Biology 23 (4): 625 – 633. https://doi.org/10.1016/S0301-5629(97)00042-2