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Cheng-Guo Wu

Institution
University of Wisconsin, Madison
ORCID
ORCID logo 0000-0003-0514-6474

Projects

Decommissioning of protein phosphatase 2A holoenzymes

Lead Institution
University of Wisconsin, Madison
Principal Investigator
Yongna Xing
Protein phosphatase 2A (PP2A) is a major tumor suppressor and plays a critical role in many essential cellular processes via formation of diverse heterotrimeric holoenzymes. Each holoenzyme contains…

Structural Mechanism of Jordan's Syndrome

Lead Institution
University of Wisconsin, Madison
Principal Investigator
Yongna Xing
Protein phosphatase 2A (PP2A) is an essential and major serine/threonine phosphatase in all eukaryotic cells, and regulates multiple cellular processes and signaling events. Deregulation of PP2A and…