Chengliang Wang

University of Connecticut

Projects

Structural and mechanistic elucidation of non-canonical inflammasome signaling

Lead Institution

University of Connecticut

Principal Investigator

Jianbin Ruan

Caspase-4/-5/-11 non-canonical inflammasomes have been known to play pivotal roles in various inflammatory and infectious diseases, such as sepsis. Current studies demonstrate that caspase-4/-5/-11…