Christopher Mcknight

Boston University School of Medicine

Projects

NMR Assignment & Structure of the C-Terminal Domains of Human Villin

Lead Institution

Boston University School of Medicine

Principal Investigator

Christopher Mcknight

Project type

Capability Research

Proteins are often composed of modular domains and NMR is uniquely suited to exploring the solution structure and dynamics of interactions between moderately sized domains. We are interested in…

Interactions Between Domains in Dematin, a Key Component of the Red Blood Cell Junctional Complex.

Lead Institution

Boston University School of Medicine

Principal Investigator

Christopher Mcknight

Project type

Large-Scale EMSL Research

The regulation and maintenance of the actin cytoskeleton is essential for all eukaryotic cells. The "villin-type headpiece" family of actin-associated proteins contains a modular C…