Claudia Jette

California Institute of Technology

0000-0002-5085-8027

Projects

Structural studies of antibodies and CD4-mimetic compounds that influence HIV-1 Env conformation

Lead Institution

California Institute of Technology

Principal Investigator

Pamela Bjorkman

The HIV-1 envelope glycoprotein (Env), a homotrimer of gp120-gp41 heterodimers, changes its conformation to mediate fusion of the host and viral membrane bilayers, the first step in infection that…