Daniel Leonard

Case Western Reserve University

0000-0002-3362-0367

Projects

Targeting the PP2A phosphatome with structure-based drug design and a selective heterotrimeric binding pocket.

Lead Institution

Case Western Reserve University

Principal Investigator

Derek Taylor

A major serine/threonine phosphatase, Protein Phosphatase 2A (PP2A), is responsible for the majority of cellular phosphatase activity under physiologic conditions and is dysregulated in an array of…