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Dawn Wenzel

Institution
University of Washington

Projects

Mechanisms of Ubiquitin Transfer and Regulation

Lead Institution
University of Washington
Principal Investigator
Rachel Klevit
Project type
Large-Scale EMSL Research
Protein ubiquitination is a powerful regulatory process that influences nearly every aspect of eukaryotic cell biology. Pathways ranging from cell-cycle progression and differentiation to DNA repair…

NMR Structural Investigations of BRCA1

Lead Institution
University of Washington
Principal Investigator
Rachel Klevit
Project type
Capability Research
The breast and ovarian cancer tumor suppressor protein, BRCA1, supports a number of fundamental cellular processes. Its absence during embryogenesis is lethal. Loss of function in proliferating…

NMR Structural Investigations of BRCA1

Lead Institution
University of Washington
Principal Investigator
Rachel Klevit
Project type
Capability Research
The breast and ovarian cancer tumor suppressor protein, BRCA1, supports a number of fundamental cellular processes. Its absence during embryogenesis is lethal. Loss of function in proliferating…