Gary Daughdrill

NMR Studies of the Dynamics of Disordered and Folded States: Isolated and Recombined Fragments from E. coli Thioredoxin.

Lead Institution

New York University

Principal Investigator

Maria Tasayco

Project type

Capability Research

This cooperative project brings together the experience of Dr. Tasayco to design, engineer, generate protein fragments and conduct complementary biophysical experiments to compare the folding of Trx…

The Evolution of Protein Flexibility

Lead Institution

University of Idaho

Principal Investigator

Gary Daughdrill

Project type

Capability Research

When novel genes are sequenced their structure and function can often be reliably predicted based on sequence similarity and evolutionary relationships to proteins with known structures. Currently,…

The Evolution of Protein Flexibility

Lead Institution

University of Idaho

Principal Investigator

Gary Daughdrill

Project type

Capability Research

The Evolution of Protein Flexibility Gary W. Daughdrill and David F. Lowry Motivation When novel genes are sequenced their structure and function can often be reliably predicted based on sequence…

Biasing conformational mobility of unstructured proteins by macromolecular crowding

Lead Institution

University of Idaho

Principal Investigator

Gary Daughdrill

Project type

Limited Scope

Macromolecular crowding is an entropic, excluded volume effect that occurs in the presence of inert macromolecules and has both thermodynamic and hydrodynamic consequences. The primary thermodynamic…

EMSL Science Overview

Gary Daughdrill

Projects

NMR Studies of the Dynamics of Disordered and Folded States: Isolated and Recombined Fragments from E. coli Thioredoxin.

The Evolution of Protein Flexibility

The Evolution of Protein Flexibility

Biasing conformational mobility of unstructured proteins by macromolecular crowding