Jessica Fernandes Scortecci

The University of British Columbia

0000-0002-9734-3477

Projects

Structural Analysis of human retinal ABCA4 using single particle cryo-electron microscopy

Lead Institution

University of British Columbia

Principal Investigator

Robert Molday

Stargardt disease (STGD1) is an autosomal recessive, early-onset macular dystrophy associated with reduced visual acuity and a progressive loss in vision. The gene responsible for STGD1 encodes ABCA4…

Structural characterization of protozoa Hsp100 by single-particle cryo-transmission electron microscopy (Cryo-TEM).

Lead Institution

Sao Carlos Institute of Chemistry, University of São Paulo

Principal Investigator

Julio Borges

Chaperones, such as Hsp100, can help maintain cellular homeostasis and adaptation playing an important role for different organisms. The Hsp100 has a disaggregase action, acting with other proteins…