Kacper Rogala

Stanford University

0000-0001-5997-7770

Projects

Conformational changes in Rag GTPases orchestrate signaling activities of mTORC1

Lead Institution

Whitehead Institute

Principal Investigator

David Sabatini

The mTORC1 protein kinase is a growth regulator that responds to stimuli, including nutrients and growth factors. Amino acids promote its translocation to the lysosomal surface, where it interacts…