Katherine Williams

University of California, San Francisco

Projects

Proteome Analysis of a Breast Carcinoma Cell Line Overexpressing the HER2/neu Oncogene

Lead Institution

University of California, San Francisco

Principal Investigator

Katherine Williams

Project type

Exploratory Research

The application of stable-isotope labeling enables accurate quantitation of relative protein levels. A key aspect of our approach will be the use of isotopically labeled polypeptides, allowing two…

Protein Signatures of Leukemic Cells

Lead Institution

University of California, San Francisco

Principal Investigator

Katherine Williams

Project type

Exploratory Research

The objective of this project is to determine whether differences in protein expression in acute promyelocytic leukemia with a t(15;17) segregate with treatment outcome. The strategy to identify…

Identification and relative expression of membrane proteins in breast cancer cell lines

Lead Institution

University of California, San Francisco

Principal Investigator

Anil Patwardhan

Project type

Exploratory Research

Overview Phase 1: Protein identification in the ?sub-proteome? mixtures from these cell lines will be accomplished using a combination of separation techniques, LC-ESI-MS/MS, and database search and…