Kerui Xu

Pan-Omics Technology Development, Implementation, and Application to GSP Systems Biology Research

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Joshua Adkins

The BER Genome Science Program aims to understand complex biological and environmental systems across spatial and temporal scales to develop predictive knowledge relevant to DOE mission challenges…

Single-Bacterium Transcriptomics Using Nanoliter Microfluidic Droplets

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

RNA-seq has been emerging as an advanced approach to the characterization and quantification of transcriptomes using next-generation sequencing technologies. Nevertheless, most studies target to…

High-Throughput Multidimensional Bioseparations for Next-Generation Proteomics

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

Mass spectrometry (MS)-based analysis of complex biological samples is essential for biological research including the study of microbiomes. The quality of the analysis is determined not only by the…

In-Depth Proteome Mapping of the Tumor Microenvironment with Single-Cell Resolution

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

The development of effective therapies for cancer requires a deep molecular understanding of tumor heterogeneity by advanced omics technologies with spatially resolved measurements. Unfortunately,…

EMSL Science Overview

Kerui Xu

Projects

Pan-Omics Technology Development, Implementation, and Application to GSP Systems Biology Research

Single-Bacterium Transcriptomics Using Nanoliter Microfluidic Droplets

High-Throughput Multidimensional Bioseparations for Next-Generation Proteomics

In-Depth Proteome Mapping of the Tumor Microenvironment with Single-Cell Resolution