Maowei Dou

Environmental Molecular Sciences Laboratory

Projects

In-Depth Proteome Mapping of the Tumor Microenvironment with Single-Cell Resolution

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

The development of effective therapies for cancer requires a deep molecular understanding of tumor heterogeneity by advanced omics technologies with spatially resolved measurements. Unfortunately,…

Single-Bacterium Transcriptomics Using Nanoliter Microfluidic Droplets

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

RNA-seq has been emerging as an advanced approach to the characterization and quantification of transcriptomes using next-generation sequencing technologies. Nevertheless, most studies target to…

High-Throughput Multidimensional Bioseparations for Next-Generation Proteomics

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

Mass spectrometry (MS)-based analysis of complex biological samples is essential for biological research including the study of microbiomes. The quality of the analysis is determined not only by the…