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Peter Doherty

Institution
St. Jude Children's Research Hospital

Projects

Targeted identification of epigenetic determinants of T cell memory

Lead Institution
University of Tennessee
Principal Investigator
Heather Smallwood
Project type
Large-Scale EMSL Research
The ability to recognize previously encountered pathogens and rapidly eliminate them is critical to the immune system, as well as vaccine efficacy. A minute fraction of the millions of T cells…

Immunodominance hierarchies in influenza specific CD8+ T cell responses

Lead Institution
University of Tennessee
Principal Investigator
Heather Smallwood
Project type
Large-Scale EMSL Research
The phenomenon of immunodominance has been observed in B cell, CD4+ T cell and CD8+ T cell antigen-specific responses in virtually all types of infection and in tumor immunity model. It is still…