Priscilla Moore

Correlation of Structure and Function of Zinc Metalloproteins Via a Combined NMR/Molecular Theory Approach

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Andrew Lipton

Project type

Large-Scale EMSL Research

One of the most significant challenges in the metallobiochemistry of Zn2+ is the a priori determination of how the metal center will facilitate a particular chemical reaction. Two examples…

Low Temperature (10K) 25Mg Solid-State NMR of DNA Repair Proteins and Their
Complexes

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Paul Ellis

Project type

Large-Scale EMSL Research

The chemistry central to the function of the DNA repair proteins apurinic/apyrimidic endonuclease 1 (APE1) and polymerase &#946; (Pol &#946;) is the chemistry of water activated by Mg2+…

Genomes-to-Life Protein Complex Isolation Capability

Lead Institution

Western University of Health Sciences

Principal Investigator

Thomas Squier

Project type

Exploratory Research

We have established a pilot proteomics facility in support of the "Goal 1" of the Department of Energy's Genomes to Life program, which seeks to identify 80% of the protein complexes…

EMSL Science Overview

Priscilla Moore

Projects

Correlation of Structure and Function of Zinc Metalloproteins Via a Combined NMR/Molecular Theory Approach

Low Temperature (10K) 25Mg Solid-State NMR of DNA Repair Proteins and Their
Complexes

Genomes-to-Life Protein Complex Isolation Capability

Projects

Correlation of Structure and Function of Zinc Metalloproteins Via a Combined NMR/Molecular Theory Approach

Low Temperature (10K) 25Mg Solid-State NMR of DNA Repair Proteins and Their Complexes

Genomes-to-Life Protein Complex Isolation Capability

Low Temperature (10K) 25Mg Solid-State NMR of DNA Repair Proteins and Their
Complexes