Qing Yao

California Institute of Technology

0000-0003-3575-9909

Projects

Looking at the high-resolution structure of IRE1 inside cells using sub-tomogram averaging

Lead Institution

California Institute of Technology

Principal Investigator

Grant Jensen

The primary objective of our proposal is to image IRE1 foci using high-resolution cellular electron cryo-tomography (ECT). IRE1 is a member of the unfolded protein response (UPR). The UPR is an…

Dissecting bacterial secretion systems in situ with electron cryo-tomography

Lead Institution

California Institute of Technology

Principal Investigator

Grant Jensen

Pathogenic bacteria use specialized “nanomachines” to identify and interact with host cells. These machines are attractive drug targets because they are surface-exposed, widespread, and vital for…