Sadeem Ahmad

Boston Children's Hospital

0000-0003-4258-2881

Projects

Structural insights into the regulation of MDA5-mediated antiviral signaling activity

Lead Institution

Boston Children's Hospital

Principal Investigator

Sun Hur

Effective antiviral immunity involves the recognition of viral dsRNA by the innate immune receptor MDA5 and the subsequent interferon signaling cascade. Aberrant recognition of endogenous “self” RNAs…