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Tsui-Fen Chou

Institution
California Institute of Technology

Projects

Cryo-EM of the disease mutant p97 bound with its cofactor p47

Lead Institution
Arizona State University
Principal Investigator
Po-Lin Chiu
Mutation in p97/VCP (valosin-containing protein), an ATPase associated with diverse cellular activities, has been implicated in IBMPFD/ALS, which currently does not have an effective medical…