Vadim Molodtsov

Rutgers University

0000-0003-3002-4794

Projects

Transcription: Structural Basis of Promoter Escape

Lead Institution

Rutgers University

Principal Investigator

Richard Ebright

We propose to define the structural and mechanistic basis of promoter escape in bacterial transcription initiation by use of single-particle-reconstruction cryo-EM to determine structures of a set of…

Single-particle cryo-EM structural analysis of Q-dependent transcription antitermination

Lead Institution

Rutgers University

Principal Investigator

Richard Ebright

The transcription antitermination factor Q, produced by lambdoid bacteriophages, is a textbook example of a regulator of gene expression that functions at the level of transcription termination. Q…