Alexis Rohou

Genentech, Inc.

0000-0002-3343-9621

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Structural characterization of TRPA1 ion channel in complex with selective agonists

Lead Institution

Genentech, Inc.

Principal Investigator

Alexis Rohou

Our aim is to determine the structures of agonists bound to TRPA1, a ligand-gated ion channel and polymodal receptor implicated in pain, itch and respiratory diseases. Electrophilic agonists, such…