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Carlos Escalante

Institution
Virginia Commonwealth University

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
James Evans
PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

CryoEM Studies of AAV Rep-DNA complexes underlying AAV life cycle.

Lead Institution
Virginia Commonwealth University
Principal Investigator
Carlos Escalante
Adeno-associated virus (AAV) non-structural Rep proteins carry out all DNA transactions that regulate the AAV life cycle. They share two multifunctional domains: an N-terminal origin binding/nicking…