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Colleen Noviello

Institution
University of Texas Southwestern Medical Center
ORCID
ORCID logo 0000-0002-0055-1019

Projects

Cryo-EM studies of nicotinic acetylcholine receptors

Lead Institution
University of Texas Southwestern Medical Center
Principal Investigator
Ryan Hibbs
Nicotinic acetylcholine receptors mediate fast chemical neurotransmission throughout the central and peripheral nervous systems. Nicotinic receptors in the brain are the first point of action…

Structural biology of synaptic and extrasynaptic GABAA receptors

Lead Institution
University of Texas Southwestern Medical Center
Principal Investigator
Ryan Hibbs
GABAA receptors are pentameric ligand-gated ion channels and mediate the majority of fast inhibitory signaling in the brain. Here we propose to characterize the structural pharmacology of receptors…