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David Sauer

Institution
New York University School of Medicine

Projects

Structures of secondary membrane transporters

Lead Institution
New York University School of Medicine
Principal Investigator
Da-Neng Wang
We will aim to determine the structures of two membrane transporters. (I) Na+-free form of the Na+-dependent dicarboxylate transporter VcINDY, a bacterial homolog of the human liver citrate…

Structural studies of a bacterial dicarboxylate transporter

Lead Institution
New York University School of Medicine
Principal Investigator
Da-Neng Wang
Human cells import citrate as an energy source through the sodium driven citrate transporter NaCT in the plasma membrane. A bacterial homolog of NaCT is the Vibro succinate transporter VcINDY. We aim…

Structures of secondary membrane transporters

Lead Institution
New York University School of Medicine
Principal Investigator
Da-Neng Wang
We aim to determine the structures of several nutrient and drug transporter proteins. These membrane transporters play major physiological or pharmacological roles, and high resolution structural…