Dongxue Yang

Oregon Health & Science University

0000-0001-7128-9831

Projects

Cryo-EM studies of the human biogenic amine transporters

Lead Institution

Oregon Health & Science University

Principal Investigator

Eric Gouaux

The aims of the proposed research are to elucidate the first structure of the human dopamine transporter (hDAT) as well as to determine multiple structures of the human serotonin transporter (hSERT)…

Structural basis for recognition of receptor CSPG4 by Clostridium difficile toxin B

Lead Institution

University of California, Irvine

Principal Investigator

Rongsheng Jin

Clostridium difficile (C. diff) is an opportunistic pathogen, which establishes in the colon when the gut microbiota is disrupted by antibiotics or diseases. C. difficile infection (CDI) leads to…

Cryo-EM study of human serotonin transporter in complex with serotonin

Lead Institution

Oregon Health & Science University

Principal Investigator

Eric Gouaux

The objectives of this research are to elucidate the structures of a human serotonin transporter by single particle cryo-EM in multiple distinct conformational states in which the transporter is…