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Drew Gingerich

Institution
Oregon Health & Science University
ORCID
ORCID logo 0000-0001-7039-9369

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
James Evans
PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Transcription: Structural Basis of Promoter Escape

Lead Institution
Rutgers University
Principal Investigator
Richard Ebright
We propose to define the structural and mechanistic basis of promoter escape in bacterial transcription initiation by use of single-particle-reconstruction cryo-EM to determine structures of a set of…

Cell envelope characterization of members of the phylum Chlorobi

Lead Institution
University of British Columbia
Principal Investigator
Elitza Tocheva
Modern bacteria can be divided into two main groups based on their cell envelope architecture: monoderm and diderm. Typically, monoderm bacteria are surrounded by a single lipid bilayer and a thick…

Cryo-EM studies on C-type Inactivation in Kv channels

Lead Institution
Oregon Health & Science University
Principal Investigator
Francis Valiyaveetil
Voltage gated K+ (Kv) channels discriminate K+ from Na+ in the selectivity filter, which consists of four K+ binding sites. In addition to the selective conduction of K+, the selectivity filter…

Structure of an acid-sensing ion channel in a lipid environment.

Lead Institution
Oregon Health & Science University
Principal Investigator
Eric Gouaux
Acid-sensing ion channels (ASICs) are voltage-insensitive and proton-gated members of the Na-selective epithelial sodium channel/degenerin (ENaC/DEG) superfamily of ion channels and are expressed…