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Gary Holtom

Institution
Harvard University

Projects

Image Iron Oxide Nanoparticles

Lead Institution
Harvard University
Principal Investigator
Gary Holtom
Project type
Exploratory Research
Small particles (50-300 nm) particles of various iron oxides have been synthesized. These tend to aggregate and we would like to learn the size distribution of the particles and, if possible, if…

Process images produced by MRM/confocal and CARS/TPC microscopes

Lead Institution
Harvard University
Principal Investigator
Gary Holtom
Project type
Exploratory Research
Access to AFS and SDA is required for substantial bodies of data collected in collaboration with MR Imaging and Cell Biology coworkers. Some custom software (Chris Parkinson) will be used but at the…

Image iron oxide nanoparticles

Lead Institution
Harvard University
Principal Investigator
Gary Holtom
Project type
Exploratory Research
Small particles (50-300 nm) particles of various iron oxides have been synthesized. These tend to aggregate and we would like to learn the size distribution of the particles and, if possible, if…

electron induced low-dose hypersensetivity

Lead Institution
Wayne State University
Principal Investigator
Michael Joiner
Project type
Exploratory Research
Following very low acute radiation exposures, an increase in radiosensitivity has been detected at doses below 1 Gy in a number of cell lines in vitro. This phenomenon is termed ?low-dose hyper…

Electron Induced Genomic Instability

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
William Morgan
Project type
Exploratory Research
Electron induced genomic instability will be investigated using the PNNL microbeam and cho transfected gfp reporter constructs.

Fluorescence Microscopy of Cells and Particles.

Lead Institution
Harvard University
Principal Investigator
Gary Holtom
Project type
Exploratory Research
Response of live cells to particles will be studied by analyzing images taken with the fluorescence microscope.

Development of Multi-Functional Microscopy (MFM) for Cancer and AIDS Research

Lead Institution
National Cancer Institute - Frederick
Principal Investigator
Stephen Lockett
Project type
Exploratory Research
The goal of this project is to advance technology for studying complex molecular mechanisms at the cell and tissue levels. Such mechanisms underlie the processes of carcinogenesis, HIV infection and…

Development of Cell Permeable Dyes for in-vivo Live Cell Imaging

Lead Institution
Western University of Health Sciences
Principal Investigator
Thomas Squier
Project type
Exploratory Research
. Our long-term goal is to develop the necessary reagents and technology for the rapid identification of a substantial fraction of the multiprotein complexes in an organism, thereby permitting a…