Gaurav Sahay

Oregon State University

0000-0003-1071-0500

Projects

Investigation of Lipid Nanoparticle Internal Structure and Its Effect on Epithelial Cell Transfection

Lead Institution

Oregon State University

Principal Investigator

Gaurav Sahay

Lipid-based nanoparticles (LNPs) are a highly efficient way to encapsulate and safely transport nucleic acids past the cellular wall. In the last decade, nucleic acid therapeutics have expanded…

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Structural Polymorphism of Solid Lipid Nanoparticles (LNPs) containing Natural Cholesterol Analogs

Lead Institution

Oregon State University

Principal Investigator

Gaurav Sahay

Lipid-based nanoparticles (LNPs) are the most advanced nanotherapeutics for the delivery of ribonucleic acids (RNA) for gene therapy. They are the only nanoparticles being used in the clinic for RNA…