Jiayi Wang

University of Washington

0000-0002-7762-8037

Projects

Novel AI approach to unravel complex protein folding landscapes: towards better bioeconomy

Lead Institution

Chalmers University of Technology

Principal Investigator

Pernilla E L Wittung-Stafshede

Project type

Large-Scale EMSL Research

Many proteins, especially enzymes, need to bind metal ion cofactors, or gain other posttranslational modifications (PTM), to be active. None of these processes are static; protein structures are…

Virtual Proteomics (ViP): Integrative modeling of protein assemblies in a cell with constraints from proteomic data and reconstructed images from cryo-electron tomography

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Margaret Cheung-Wyker

The objective of the proposed research is to advance the spatial knowledge of higher-order protein assemblies in a cell by integrating improved image reconstruction from cryo-electron tomography and…