Skip to main content

Makayla Freitas

Institution
Oregon Health & Science University

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
James Evans
PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Structure of an acid-sensing ion channel in a lipid environment.

Lead Institution
Oregon Health & Science University
Principal Investigator
Eric Gouaux
Acid-sensing ion channels (ASICs) are voltage-insensitive and proton-gated members of the Na-selective epithelial sodium channel/degenerin (ENaC/DEG) superfamily of ion channels and are expressed…

Structure and activation mechanism of TMEM206

Lead Institution
Oregon Health & Science University
Principal Investigator
Eric Gouaux
Proton activated channels are ion-permeable channels that are rapidly activated by extracellular acidification. With their activation levels falling well below physiological pH, these channels…