Nolann Williams

Roles for Membrane Receptors in Cellular Responses to External Cues; The Case of ErbB4 and Morphology Dynamics

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Galya Orr

Project type

Large-Scale EMSL Research

This proposal is a continuation of research pursued under EMSL User Proposal #22092. Understanding the mechanisms that underlie the cellular responses to the environment has been the subject of…

Nanoscale Characterization of Nanomaterial - Cell Interactions

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Galya Orr

Project type

Large-Scale EMSL Research

This proposal is a continuation of research pursued under EMSL User Proposal #17690. The extensive use of amorphous silica nanoparticles (NPs) in the industry, and the growing use of carbon nanotubes…

Pathways and fate of individual nanoparticles in vivo; a whole organism approach

Lead Institution

Oregon State University

Principal Investigator

Robert Tanguay

Project type

Large-Scale EMSL Research

The growing commerce in micro- and nanotechnology is expected to increase human exposure to submicrometer and nanoscale particles, including certain forms of amorphous silica nanoparticles. Adverse…

Nanoparticle-Cell Interactions and Intracellular Fate; Roles of Particle Surface Properties

Lead Institution

Oregon State University

Principal Investigator

Bettye Maddux

Project type

Large-Scale EMSL Research

The growing commerce in micro- and nanotechnology is expected to increase human exposure to submicrometer and nanoscale particles, including certain forms of gold and amorphous silica. Adverse…

Physicochemical determinants of distribution and fate of nanoparticles following in vivo exposure

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Justin Teeguarden

Project type

Large-Scale EMSL Research

The risks associated with the use of nanomaterials have been recently under investigation (1) as increasingly more nanosized products are developed and commercialized. The advent of nanotoxicology as…

Development of Novel Approaches for Analysis of Secondary Organic Aerosols
Using High-Resolution Mass Spectrometry.

Lead Institution

Purdue University

Principal Investigator

Alexander Laskin

The objective of the proposed research is to develop new approaches for advanced detailed characterization of the chemical composition of organic aerosols (OA) that will enable a fundamental…

Tying Distinct Nanoparticle Properties to Cell Surface Interactions and Intracellular Fate

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Joel Pounds

Project type

Large-Scale EMSL Research

The increasing use of engineered nanomaterials in industrial and medical applications is expected to increase both unintended environmental or occupational exposures and intended medical or direct…

EMSL Science Overview

Nolann Williams

Projects

Roles for Membrane Receptors in Cellular Responses to External Cues; The Case of ErbB4 and Morphology Dynamics

Nanoscale Characterization of Nanomaterial - Cell Interactions

Pathways and fate of individual nanoparticles in vivo; a whole organism approach

Nanoparticle-Cell Interactions and Intracellular Fate; Roles of Particle Surface Properties

Physicochemical determinants of distribution and fate of nanoparticles following in vivo exposure

Development of Novel Approaches for Analysis of Secondary Organic Aerosols
Using High-Resolution Mass Spectrometry.

Tying Distinct Nanoparticle Properties to Cell Surface Interactions and Intracellular Fate