Noopur Sharma

Multi-scale investigation of the nitrogen fixation mechanism of Mo-dependent nitrogenase

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Simone Raugei

Project type

Large-Scale EMSL Research

We propose to use EMSL NMR and supercomputing resources to gain a molecular level understanding of how substrate binding, electron, and proton delivery is controlled by the nitrogenase metalloenzyme…

Structural Dynamics of Plant Cellulose Synthesis & Assembly Revealed by CryoTEM and DTEM

Lead Institution

Pennsylvania State University

Principal Investigator

Bryan Nixon

Project type

Large-Scale EMSL Research

We propose to capitalize on preliminary work defining in vitro cellulose synthesis from membrane protein purified from the nonvascular plant Physcomitrella patens. This system grants access to…

Systems Biology Through an Integrated Multimodal Imaging and Analysis Framework

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

Organisms have evolved a number of spatially localized processes to efficiently break down, absorb, and use necessary metabolites. Although progress has been made in identifying the genes that are…

Atomistic simulations of the nitrogen fixation by Mo-dependent nitrogenase

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Simone Raugei

Project type

Large-Scale EMSL Research

We propose to use EMSL supercomputing resources to gain a molecular level understanding of how substrate binding, electron, and proton delivery are controlled by the nitrogenase metalloenzyme to…

Unraveling New Pathways for Carbon Capture to Enhance Lipid-Biomass Feedstocks

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

Organisms have evolved a number of spatially localized processes to efficiently break down, absorb, and use necessary metabolites. Although progress has been made in identifying the genes that are…

EMSL Science Overview

Noopur Sharma

Projects

Multi-scale investigation of the nitrogen fixation mechanism of Mo-dependent nitrogenase

Structural Dynamics of Plant Cellulose Synthesis & Assembly Revealed by CryoTEM and DTEM

Systems Biology Through an Integrated Multimodal Imaging and Analysis Framework

Atomistic simulations of the nitrogen fixation by Mo-dependent nitrogenase

Unraveling New Pathways for Carbon Capture to Enhance Lipid-Biomass Feedstocks