Pamela Bjorkman

California Institute of Technology

0000-0002-2277-3990

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Structural studies of antibodies and CD4-mimetic compounds that influence HIV-1 Env conformation

Lead Institution

California Institute of Technology

Principal Investigator

Pamela Bjorkman

The HIV-1 envelope glycoprotein (Env), a homotrimer of gp120-gp41 heterodimers, changes its conformation to mediate fusion of the host and viral membrane bilayers, the first step in infection that…