Sabeeha Merchant

Absolute quantification of components of the algal photosynthetic apparatus in response to environment and modification of chlorophyll biosynthesis

Lead Institution

University of California, Berkeley

Principal Investigator

Sabeeha Merchant

Project type

Large-Scale EMSL Research

The operation of the photosynthetic apparatus is influenced by environment, particularly stress situations like poor iron nutrition, carbon or light limitation, and excess excitation energy, which…

Stoichiometry changes to photosynthetic structures in algae in response to environmental stimuli and genetic engineering

Lead Institution

University of California, Berkeley

Principal Investigator

Sabeeha Merchant

Project type

Exploratory Research

Photosynthesis is essential for all life on Earth, with the photosynthetic electron transfer chain and the Calvin-Benson cycle being the key molecular machineries assimilating inorganic carbon with…

The knowns against the unknowns: Photosynthesis gene discovery through multi-omic survey of photosynthetic mutants during light stress

Lead Institution

Lawrence Berkeley National Laboratory

Principal Investigator

Setsuko Wakao

Project type

Large-Scale EMSL Research

To advance genome-based understanding of photosynthesis, we have generated a high-quality, phenotyped photosynthesis mutant library in the model unicellular green alga, Chlamydomonas reinhardtii…

Histone dynamics during the life cycle of Chlamydomonas

Lead Institution

Donald Danforth Plant Science Center

Principal Investigator

James Umen

Project type

Large-Scale EMSL Research

Diurnal cycles are central drivers of gene expression in photosynthetic organisms including cyanobacteria, algae and land plants. The model unicellular green alga Chlamydomonas reinhardtii has…

Proteomic view of the iron deficiency response in Dunaliella

Lead Institution

University of California, Berkeley

Principal Investigator

Sabeeha Merchant

Project type

Large-Scale EMSL Research

Algae are responsible for half of global primary productivity and have an important role in biogeochemical cycling. Algae can thrive in nutrient-rich and nutrient-depleted environments, indicating…

Systems Analysis of Trophic Transitions in Chromochloris zofingiensis, an Emerging Model Green Alga with Promising Biofuel Potential

Lead Institution

University of California, Berkeley

Principal Investigator

Krishna Niyogi

Project type

FICUS Research

As a core component of a sustainable bio-economy, microalgae have the potential to become a major source of biofuels and bioproducts without exacerbating environmental problems. These photosynthetic…

Managing the cellular zinc economy: proteomics-enabled predictive understanding of zinc hierarchy

Lead Institution

Lawrence Berkeley National Laboratory

Principal Investigator

Crysten Blaby

Project type

Large-Scale EMSL Research

Zinc is an essential nutrient in biology. When encountering environments with suboptimal zinc availability, organisms initiate acclimation strategies that operate to increase assimilation and release…

Gene function discovery in photosynthesis: A multi-omics approach

Lead Institution

University of California, Berkeley

Principal Investigator

Sabeeha Merchant

Project type

FICUS Research

Photosynthesis is the defining characteristic of plants enabling the capture and transformation of sunlight into bioenergy and has been the focus of plant research for centuries. Remarkably, whole…

The Diurnal Redox Proteome of Chlamydomonas

Lead Institution

Michigan State University

Principal Investigator

Daniela Strenkert

Project type

Large-Scale EMSL Research

Nearly all organisms exhibit diurnal metabolic cycles, especially phototrophs, whose metabolism is strictly dependent on light. Transcriptomics experiments in cyanobacteria, algae and plants have…

Dissecting Fe Driven Changes to Metabolism in Photosynthetic Eukaryotes

Lead Institution

Michigan State University

Principal Investigator

Stefan Schmollinger

Project type

Large-Scale EMSL Research

Iron (Fe) is an essential micronutrient for nearly all forms of life, because of its vital role in respiration, photosynthesis, central carbon metabolism, as well as other reactions involving…

Investigating Oiliness: Systems Comparison of Photoautotrophic and Heterotrophic Lipid Production in Auxenochlorella protothecoides.

Lead Institution

University of California, Berkeley

Principal Investigator

Jeffrey Moseley

Project type

Large-Scale EMSL Research

Auxenochlorella protothecoides is a photosynthetic, Trebouxiophyte alga, with a small, highly compact nuclear genome. Auxenochlorella strains are highly oleaginous, accumulating up to 60% of dry…

A day in the life of Chlamydomonas and its neighbors: Systems analysis of a microbial phototroph-heterotroph symbiosis

Lead Institution

University of California, Berkeley

Principal Investigator

Sabeeha Merchant

Project type

FICUS Research

Phytoplankton, which rely on the sun for energy, are responsible for roughly half of global primary productivity. These organisms dramatically change their metabolic strategy in the night when…

The proteome of a day in the life of Chlamydomonas

Lead Institution

University of California, Berkeley

Principal Investigator

Sabeeha Merchant

Project type

Large-Scale EMSL Research

Nearly all organisms exhibit diurnal metabolic cycles. In photosynthetic organisms, light is a key input into metabolic cycles. Transcriptomics experiments in cyanobacteria, algae and plants have…

EMSL Science Overview

Sabeeha Merchant

Projects

Absolute quantification of components of the algal photosynthetic apparatus in response to environment and modification of chlorophyll biosynthesis

Stoichiometry changes to photosynthetic structures in algae in response to environmental stimuli and genetic engineering

The knowns against the unknowns: Photosynthesis gene discovery through multi-omic survey of photosynthetic mutants during light stress

Histone dynamics during the life cycle of Chlamydomonas

Proteomic view of the iron deficiency response in Dunaliella

Systems Analysis of Trophic Transitions in Chromochloris zofingiensis, an Emerging Model Green Alga with Promising Biofuel Potential

Managing the cellular zinc economy: proteomics-enabled predictive understanding of zinc hierarchy

Gene function discovery in photosynthesis: A multi-omics approach

The Diurnal Redox Proteome of Chlamydomonas

Dissecting Fe Driven Changes to Metabolism in Photosynthetic Eukaryotes

Investigating Oiliness: Systems Comparison of Photoautotrophic and Heterotrophic Lipid Production in Auxenochlorella protothecoides.

A day in the life of Chlamydomonas and its neighbors: Systems analysis of a microbial phototroph-heterotroph symbiosis

The proteome of a day in the life of Chlamydomonas