Shiyu Xia

Boston Children's Hospital

0000-0001-9024-0689

Projects

COVID-19: Structural study of RNA-dependent RNA polymerase of SARS-CoV-2

Lead Institution

Boston Children's Hospital

Principal Investigator

Hao Wu

The outbreak of COVID-19 by SARS-CoV-2 infection has induced a global health crisis with millions of infections and about 20 thousand deaths. The replication of SARS-CoV-2 is dependent on RNA…

Mechanistic elucidation of inflammasome biology

Lead Institution

Boston Children's Hospital

Principal Investigator

Hao Wu

Innate immunity comprises ancient and evolutionarily conserved biological pathways that are imperative for the recognition of pathogens and endogenous damage. One such major signaling pathway…