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Show-Ling Shyng

Institution
Oregon Health & Science University
ORCID
ORCID logo 0000-0002-8230-8820

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
James Evans
PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

KATP channel structures

Lead Institution
Oregon Health & Science University
Principal Investigator
Show-Ling Shyng
ATP-sensitive potassium (KATP) channels couple cell metabolism to membrane excitability and are important for regulating hormone secretion, neuronal activity, vascular tone, and adaptive response to…

CryoEM structures of pancreatic KATP channels

Lead Institution
Oregon Health & Science University
Principal Investigator
Show-Ling Shyng
The ATP-sensitive potassium (KATP) channel formed by four Kir6.2 and four SUR1 subunits regulate insulin secretion in ?-cells by coupling glucose metabolism with membrane excitability. Mutations in…