Simon White

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

James Evans

PNNL will create and operate the Pacific Northwest Center for Cryo-EM (PNCC), a state-of-the-art national center for cryo-electron microscopy (Cryo-EM) that will rapidly and efficiently collect and…

Understanding the evolution of the coat protein fold using P22-like phages

Lead Institution

University of Connecticut

Principal Investigator

Carolyn Teschke

Despite very low sequence homology, the major capsid proteins of dsDNA bacteriophages, some archaeal viruses and the herpesviruses, share a common structural motif - the HK97-fold. My group is…

Investigating the divergence of the major capsid protein within very closely related phage

Lead Institution

University of Connecticut

Principal Investigator

Simon White

The objective is to begin to understand the evolution of the HK97-like major capsid protein in the closely related actinobacteriophage (viruses that infect the Actinobacteria phylum). It will have…

EMSL Science Overview

Simon White

Projects

Collaborative Access Team: Pacific Northwest Cryo-EM Center (PNCC)

Understanding the evolution of the coat protein fold using P22-like phages

Investigating the divergence of the major capsid protein within very closely related phage